Component
Urinary zinc in selected food-color-reactive children
Experimental model, exposure and limitations remain on each linked record.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The selected food-color-reactive children had higher urinary zinc output after the tartrazine challenge.
Experimental context and source evidence
- dose
- Single 50 mg tartrazine beverage challenge
- duration
- 120 min monitoring
- evidence_access
- Primary full-text methods/results and metadata.
- evidence_scope
- literature_reviewed; source-specific experimental curation
- experimental_model
- Selected children with parent-reported food-color reactions; tartrazine group n=23, matched tartrazine control subgroup n=5
- limitations
- No placebo challenge group in this 1997 experiment; selected population and small control subgroup. The source reports significant changes, but provides no zinc balance or intracellular threshold. Association does not prove chelation, ADHD causation, or benefit from zinc supplementation.
- nutrient_topic
- Tartrazine food-colorant chapter; nutrient, drug and peptide interactions retain their models and limits. · Tartrazine
- organism
- Selected children with parent-reported food-color reactions; tartrazine group n=23, matched tartrazine control subgroup n=5
- plain_language
- The selected food-color-reactive children had higher urinary zinc output after the tartrazine challenge.
- primary_references
- Assessment of Chemical Factors in Relation to Child Hyperactivity (1997). https://doi.org/10.1080/13590849762466 DOI: 10.1080/13590849762466
- route
- Oral beverage
- tissue
- Serum and urine zinc
Tartrazine: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 292–301
Original AI-assisted curation of eighteen primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Selected children with parent-reported food-color reactions; tartrazine group n=23, matched tartrazine control subgroup n=5 · source_derived_draft · unverified_draft
## tartrazine-zinc-urine The selected food-color-reactive children had higher urinary zinc output after the tartrazine challenge. Model/species: Selected children with parent-reported food-color reactions; tartrazine group n=23, matched tartrazine control subgroup n=5 Tissue: Serum and urine zinc Exposure: Single 50 mg tartrazine beverage challenge Route: Oral beverage Duration: 120 min monitoring Limits: No placebo challenge group in this 1997 experiment; selected population and small control subgroup. The source reports significant changes, but provides no zinc balance or intracellular threshold. Association does not prove chelation, ADHD causation, or benefit from zinc supplementation. Primary reference: Assessment of Chemical Factors in Relation to Child Hyperactivity (1997). https://doi.org/10.1080/13590849762466 DOI: 10.1080/13590849762466 Access: Primary full-text methods/results and metadata.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.