Component
Cutaneous, respiratory and cardiovascular responses in atopic adults
Experimental model, exposure and limitations remain on each linked record.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The 26-adult crossover study found no significant cutaneous, respiratory or cardiovascular difference between tartrazine and placebo.
Experimental context and source evidence
- dose
- Tartrazine 35 mg versus placebo
- duration
- Acute challenge; exact observation period not in abstract
- evidence_access
- Primary PubMed abstract; unrecovered method details explicitly retained.
- evidence_scope
- literature_reviewed; source-specific experimental curation
- experimental_model
- 26 atopic adults with rhinitis, asthma, urticaria or NSAID-related reactions
- limitations
- Small study with no significant group response does not rule out rare individual intolerance.
- nutrient_topic
- Tartrazine food-colorant chapter; nutrient, drug and peptide interactions retain their models and limits. · Tartrazine
- organism
- 26 atopic adults with rhinitis, asthma, urticaria or NSAID-related reactions
- plain_language
- The 26-adult crossover study found no significant cutaneous, respiratory or cardiovascular difference between tartrazine and placebo.
- primary_references
- Safety of ingestion of yellow tartrazine by double-blind placebo controlled challenge in 26 atopic adults. (2010). https://pubmed.ncbi.nlm.nih.gov/20106580/ DOI: 10.1016/j.aller.2009.09.009
- route
- Oral administration
- tissue
- Double-blind placebo-controlled crossover challenge
Tartrazine: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 336–345
Original AI-assisted curation of eighteen primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · 26 atopic adults with rhinitis, asthma, urticaria or NSAID-related reactions · source_derived_draft · unverified_draft
## tartrazine-atopic-null The 26-adult crossover study found no significant cutaneous, respiratory or cardiovascular difference between tartrazine and placebo. Model/species: 26 atopic adults with rhinitis, asthma, urticaria or NSAID-related reactions Tissue: Double-blind placebo-controlled crossover challenge Exposure: Tartrazine 35 mg versus placebo Route: Oral administration Duration: Acute challenge; exact observation period not in abstract Limits: Small study with no significant group response does not rule out rare individual intolerance. Primary reference: Safety of ingestion of yellow tartrazine by double-blind placebo controlled challenge in 26 atopic adults. (2010). https://pubmed.ncbi.nlm.nih.gov/20106580/ DOI: 10.1016/j.aller.2009.09.009 Access: Primary PubMed abstract; unrecovered method details explicitly retained.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.