Component
Human cycling time-trial performance after astaxanthin
Context-specific entity; species, compartment and exposure are stated on each claim.
3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
In 32 well-trained male cyclists, 20 mg/day for four weeks raised plasma astaxanthin but did not improve time-trial performance or fat oxidation.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_access
- Primary abstract
- experimental_model
- Human randomized trial in trained cyclists.
- limitations
- Different dose, training status and protocol from the positive trials; these are candidate explanations, not a demonstrated reconciliation.
- nutrient_topic
- Astaxanthin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Astaxanthin
- plain_language
- Higher blood exposure did not translate into better performance.
- primary_references
- Astaxanthin supplementation does not augment fat use or improve endurance performance. · 2013 · https://pubmed.ncbi.nlm.nih.gov/23274592/ · DOI 10.1249/MSS.0b013e31827fddc4
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Astaxanthin: transport, membrane chemistry, signaling and nutrient interactions (2026-09-19) · lines 462–468
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Human randomized trial in trained cyclists. · source_derived_draft · unverified_draft
## astaxanthin-cycling-null-2013 Higher blood exposure did not translate into better performance. In 32 well-trained male cyclists, 20 mg/day for four weeks raised plasma astaxanthin but did not improve time-trial performance or fat oxidation. Model: Human randomized trial in trained cyclists. Limitations: Different dose, training status and protocol from the positive trials; these are candidate explanations, not a demonstrated reconciliation. Evidence access: Primary abstract Astaxanthin supplementation does not augment fat use or improve endurance performance. · 2013 · https://pubmed.ncbi.nlm.nih.gov/23274592/ · DOI 10.1249/MSS.0b013e31827fddc4
Complete structured claim and evidenceAfter 4 mg/day for 28 days, the astaxanthin group improved its 20-km cycling time trial more than placebo in the 14 completers of a 21-person randomized study.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Seven completers per arm; time trial after two hours of exercise.
- limitations
- Attrition and small groups limit precision; substrate oxidation did not improve.
- nutrient_topic
- Astaxanthin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Astaxanthin
- plain_language
- A small cycling study reported faster performance.
- primary_references
- Effect of astaxanthin on cycling time trial performance. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21984399/ · DOI 10.1055/s-0031-1280779
Astaxanthin: transport, membrane chemistry, signaling and nutrient interactions (2026-09-19) · lines 454–460
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Seven completers per arm; time trial after two hours of exercise. · source_derived_draft · unverified_draft
## astaxanthin-cycling-positive-2011 A small cycling study reported faster performance. After 4 mg/day for 28 days, the astaxanthin group improved its 20-km cycling time trial more than placebo in the 14 completers of a 21-person randomized study. Model: Seven completers per arm; time trial after two hours of exercise. Limitations: Attrition and small groups limit precision; substrate oxidation did not improve. Evidence access: Primary abstract Effect of astaxanthin on cycling time trial performance. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21984399/ · DOI 10.1055/s-0031-1280779
Complete structured claim and evidenceTwelve recreationally trained men completed a crossover trial of 12 mg/day for seven days; 40-km performance improved by about 1.2%, or 51 seconds on average.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Human crossover trial with 14-day washout.
- limitations
- Small sample; a reported fat-oxidation difference occurred at the final 39–40 km and should not be generalized to the entire event.
- nutrient_topic
- Astaxanthin collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Astaxanthin
- plain_language
- Another small trial found a modest performance improvement.
- primary_references
- The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. · 2021 · https://pubmed.ncbi.nlm.nih.gov/32660833/ · DOI 10.1016/j.jsams.2020.06.017
Astaxanthin: transport, membrane chemistry, signaling and nutrient interactions (2026-09-19) · lines 470–476
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Human crossover trial with 14-day washout. · source_derived_draft · unverified_draft
## astaxanthin-cycling-positive-2021 Another small trial found a modest performance improvement. Twelve recreationally trained men completed a crossover trial of 12 mg/day for seven days; 40-km performance improved by about 1.2%, or 51 seconds on average. Model: Human crossover trial with 14-day washout. Limitations: Small sample; a reported fat-oxidation difference occurred at the final 39–40 km and should not be generalized to the entire event. Evidence access: Primary abstract The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. · 2021 · https://pubmed.ncbi.nlm.nih.gov/32660833/ · DOI 10.1016/j.jsams.2020.06.017
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.