Component
Helicobacter pylori urease complex
Helicobacter pylori urease complex. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Sulforaphane caused time-dependent urease inactivation with spectroscopic evidence of cysteine-thiol adduct formation.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/sulforaphane-research/23583386.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4542d001efffa337d1aae4de7767a914ed8cd951bc5e56ded5183046abe10577", "start_char": 0, "end_char": 1843, "text_sha256": "4542d001efffa337d1aae4de7767a914ed8cd951bc5e56ded5183046abe10577"}
- experimental_model
- Purified urease assays and bacterial comparisons
- exposure
- Sulforaphane and related isothiocyanates
- limitations
- Urease inactivation was not obligatory for bacterial killing; do not portray one target as the entire antibacterial mechanism.
- nutrient_topic
- Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. · Sulforaphane / SFN, stereochemistry specified per study
- organism
- H. pylori and jack-bean urease experiments
- plain_language
- The compound can chemically inhibit a bacterial enzyme.
- primary_references
- [sulforaphane-p23583386] Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates. (2013). https://pubmed.ncbi.nlm.nih.gov/23583386/ DOI: 10.1016/j.bbrc.2013.03.126
- tissue_or_cell_type
- Urease modification and bacterial killing
Sulforaphane: formation, electrophile sensing and nutrient connections (2026-09-17) · lines 1282–1293
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified urease assays and bacterial comparisons · source_derived_draft · unverified_draft
### sulforaphane-urease-inactivation Sulforaphane caused time-dependent urease inactivation with spectroscopic evidence of cysteine-thiol adduct formation. Condition category: normal nutrient_topic: Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. plain_language: The compound can chemically inhibit a bacterial enzyme. organism: H. pylori and jack-bean urease experiments tissue_or_cell_type: Urease modification and bacterial killing experimental_model: Purified urease assays and bacterial comparisons limitations: Urease inactivation was not obligatory for bacterial killing; do not portray one target as the entire antibacterial mechanism. exposure: Sulforaphane and related isothiocyanates evidence_span: {"source_cache": "artifacts/sulforaphane-research/23583386.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4542d001efffa337d1aae4de7767a914ed8cd951bc5e56ded5183046abe10577", "start_char": 0, "end_char": 1843, "text_sha256": "4542d001efffa337d1aae4de7767a914ed8cd951bc5e56ded5183046abe10577"} [sulforaphane-p23583386] Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates. (2013). https://pubmed.ncbi.nlm.nih.gov/23583386/ DOI: 10.1016/j.bbrc.2013.03.126
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.