Component
Cognitive sequelae after acute carbon monoxide poisoning
Cognitive sequelae after acute carbon monoxide poisoning. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Cognitive sequelae at six weeks occurred in 25.0% of the hyperbaric group versus 46.1% of the normobaric group, an adjusted odds ratio of 0.45, and the difference persisted at 12 months.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/hbot-research/12362006.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f1d5366f5eb1704ebe411ee13fba05068a310070c87ae65c8c75df678655dcca", "start_char": 0, "end_char": 1966, "text_sha256": "f1d5366f5eb1704ebe411ee13fba05068a310070c87ae65c8c75df678655dcca"}
- experimental_model
- Double-blind randomised trial of 152 patients with symptomatic acute carbon monoxide poisoning
- exposure
- Three hyperbaric oxygen sessions within 24 hours versus normobaric oxygen plus sham sessions
- limitations
- A randomised double-blind trial stopped early at a planned interim analysis, which tends to overstate effect size. Cerebellar dysfunction was imbalanced at baseline and was adjusted for.
- nutrient_topic
- Hyperbaric oxygen research collection; topical membership is not evidence of a direct clinical effect, and a therapeutic exposure is not a dietary intake. · Hyperbaric oxygen therapy
- organism
- Human
- plain_language
- Fewer people had lasting thinking problems after the treatment.
- primary_references
- [hbot-p12362006] Hyperbaric oxygen for acute carbon monoxide poisoning. (2002). https://pubmed.ncbi.nlm.nih.gov/12362006/ DOI: 10.1056/nejmoa013121
- tissue_or_cell_type
- Brain
Hyperbaric oxygen: the exposure, its reactive species, the signals they carry, and the nutrient-dependent enzymes that handle them (2026-09-19) · lines 1063–1074
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind randomised trial of 152 patients with symptomatic acute carbon monoxide poisoning · source_derived_draft · unverified_draft
### hbot-co-cognitive-benefit Cognitive sequelae at six weeks occurred in 25.0% of the hyperbaric group versus 46.1% of the normobaric group, an adjusted odds ratio of 0.45, and the difference persisted at 12 months. Condition category: normal nutrient_topic: Hyperbaric oxygen research collection; topical membership is not evidence of a direct clinical effect, and a therapeutic exposure is not a dietary intake. plain_language: Fewer people had lasting thinking problems after the treatment. organism: Human tissue_or_cell_type: Brain experimental_model: Double-blind randomised trial of 152 patients with symptomatic acute carbon monoxide poisoning limitations: A randomised double-blind trial stopped early at a planned interim analysis, which tends to overstate effect size. Cerebellar dysfunction was imbalanced at baseline and was adjusted for. exposure: Three hyperbaric oxygen sessions within 24 hours versus normobaric oxygen plus sham sessions evidence_span: {"source_cache": "artifacts/hbot-research/12362006.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f1d5366f5eb1704ebe411ee13fba05068a310070c87ae65c8c75df678655dcca", "start_char": 0, "end_char": 1966, "text_sha256": "f1d5366f5eb1704ebe411ee13fba05068a310070c87ae65c8c75df678655dcca"} [hbot-p12362006] Hyperbaric oxygen for acute carbon monoxide poisoning. (2002). https://pubmed.ncbi.nlm.nih.gov/12362006/ DOI: 10.1056/nejmoa013121
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.