Component
C. zeylanicum extracts standardized to 15, 45 or 75% GAE in 2014
C. zeylanicum extracts standardized to 15, 45 or 75% GAE in 2014. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
The 45% and 75% GAE extracts showed greater hypoglycemic effects than the 15% GAE aqueous comparator in STZ-diabetic rats.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/ceylon-research/25051315.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3a6dc6fe3a75793687a15c6ce73ab8ae07dbf8541c5b329d2f35c1a42922d5bb", "start_char": 0, "end_char": 1406, "text_sha256": "3a6dc6fe3a75793687a15c6ce73ab8ae07dbf8541c5b329d2f35c1a42922d5bb"}
- experimental_model
- Extract comparison in diabetic rats plus uncontrolled human pilot
- exposure
- Rats 200 mg/kg for 30 days; 15 unmedicated adults, procynZ-45 125 mg twice daily for 30 days
- limitations
- GAE denotes assay standardization, not proof that 45% of extract mass is a single polyphenol. Human pilot lacked a randomized control.
- nutrient_topic
- Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. · Ceylon cinnamon / Cinnamomum verum bark preparations
- organism
- Rat
- plain_language
- Changing the extract changed the result; all cinnamon products cannot be treated as equivalent.
- primary_references
- [ceylon-p25051315] Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts. (2014). https://pubmed.ncbi.nlm.nih.gov/25051315/ DOI: 10.1039/c4fo00130c
- tissue_or_cell_type
- Metabolic measurements
Ceylon cinnamon: metabolism, signaling and nutrient connections (2026-09-17) · lines 1078–1089
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Extract comparison in diabetic rats plus uncontrolled human pilot · source_derived_draft · unverified_draft
### ceylon-polyphenol-rat The 45% and 75% GAE extracts showed greater hypoglycemic effects than the 15% GAE aqueous comparator in STZ-diabetic rats. Condition category: normal nutrient_topic: Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. plain_language: Changing the extract changed the result; all cinnamon products cannot be treated as equivalent. organism: Rat tissue_or_cell_type: Metabolic measurements experimental_model: Extract comparison in diabetic rats plus uncontrolled human pilot limitations: GAE denotes assay standardization, not proof that 45% of extract mass is a single polyphenol. Human pilot lacked a randomized control. exposure: Rats 200 mg/kg for 30 days; 15 unmedicated adults, procynZ-45 125 mg twice daily for 30 days evidence_span: {"source_cache": "artifacts/ceylon-research/25051315.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3a6dc6fe3a75793687a15c6ce73ab8ae07dbf8541c5b329d2f35c1a42922d5bb", "start_char": 0, "end_char": 1406, "text_sha256": "3a6dc6fe3a75793687a15c6ce73ab8ae07dbf8541c5b329d2f35c1a42922d5bb"} [ceylon-p25051315] Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts. (2014). https://pubmed.ncbi.nlm.nih.gov/25051315/ DOI: 10.1039/c4fo00130c
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.