Component
Cardiac rapidly activating delayed rectifier potassium current
Cardiac rapidly activating delayed rectifier potassium current; interpretation depends on linked experimental context.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Four weeks of 0.1% versus 0.62% dietary K produced hypokalemia, reduced ventricular IKr and prolonged corrected QT in rabbits.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- experimental_model
- Rabbit dietary experiment, four weeks.
- limitations
- Animal dietary finding does not establish human intake targets or a sole QT mechanism.
- nutrient_topic
- Potassium research collection; topical membership is not evidence of a direct dietary effect. · Potassium
- organism
- Rabbit
- plain_language
- Sustained dietary restriction affected a cardiac recovery current.
- primary_references
- [guo-2009-herg] Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines (2009). https://www.jci.org/articles/view/39027 DOI: 10.1172/JCI39027
- tissue_or_cell_type
- Ventricular myocardium
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Potassium: cross-nutrient mechanisms and deficiency (2026-09-17) · lines 704–713
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Rabbit dietary experiment, four weeks. · source_derived_draft · unverified_draft
### k-diet-rabbit-ikr Four weeks of 0.1% versus 0.62% dietary K produced hypokalemia, reduced ventricular IKr and prolonged corrected QT in rabbits. Condition category: nutrient_deficiency nutrient_topic: Potassium research collection; topical membership is not evidence of a direct dietary effect. plain_language: Sustained dietary restriction affected a cardiac recovery current. organism: Rabbit tissue_or_cell_type: Ventricular myocardium experimental_model: Rabbit dietary experiment, four weeks. limitations: Animal dietary finding does not establish human intake targets or a sole QT mechanism. [guo-2009-herg] Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines (2009). https://www.jci.org/articles/view/39027 DOI: 10.1172/JCI39027
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.