Component
Human exfoliated buccal-cell glutathione concentration
Human exfoliated buccal-cell glutathione concentration. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
High-dose buccal-cell GSH increased about 260% versus baseline at six months.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/glutathione-research/24791752.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "b65406018e3d344f25ad877adb47c73cce7431e9ba5e8d280a35aae066112388", "start_char": 0, "end_char": 1596, "text_sha256": "b65406018e3d344f25ad877adb47c73cce7431e9ba5e8d280a35aae066112388"}
- experimental_model
- Six-month randomized double-blind placebo-controlled trial
- exposure
- 250 or 1000 mg/day oral GSH; one-month washout
- limitations
- Pool increases reported relative to baseline; NK comparison was versus placebo. Biomarkers do not prove fewer illnesses or longer life.
- nutrient_topic
- Glutathione research collection; topical membership is not evidence of a direct dietary effect. · GSH
- organism
- Human
- plain_language
- The size of the change depended on the sampled compartment.
- primary_references
- [glutathione-p24791752] Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. (2015). https://pubmed.ncbi.nlm.nih.gov/24791752/ DOI: 10.1007/s00394-014-0706-z
- tissue_or_cell_type
- 54 nonsmoking adults; immune subset
Glutathione: metabolism, signaling and nutrient connections (2026-09-17) · lines 1217–1228
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Six-month randomized double-blind placebo-controlled trial · source_derived_draft · unverified_draft
### glutathione-oral-2015-buccal High-dose buccal-cell GSH increased about 260% versus baseline at six months. Condition category: normal nutrient_topic: Glutathione research collection; topical membership is not evidence of a direct dietary effect. plain_language: The size of the change depended on the sampled compartment. organism: Human tissue_or_cell_type: 54 nonsmoking adults; immune subset experimental_model: Six-month randomized double-blind placebo-controlled trial limitations: Pool increases reported relative to baseline; NK comparison was versus placebo. Biomarkers do not prove fewer illnesses or longer life. exposure: 250 or 1000 mg/day oral GSH; one-month washout evidence_span: {"source_cache": "artifacts/glutathione-research/24791752.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "b65406018e3d344f25ad877adb47c73cce7431e9ba5e8d280a35aae066112388", "start_char": 0, "end_char": 1596, "text_sha256": "b65406018e3d344f25ad877adb47c73cce7431e9ba5e8d280a35aae066112388"} [glutathione-p24791752] Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. (2015). https://pubmed.ncbi.nlm.nih.gov/24791752/ DOI: 10.1007/s00394-014-0706-z
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.