Component
Putative 1:1 boric-acid–riboflavin complex
Putative 1:1 boric-acid–riboflavin complex. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
An additional m/z 401.3 ion was consistent with a 1:1 riboflavin–boric-acid complex in alkaline electrospray experiments; the ribityl binding site was not resolved.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/boron-research/42012780.fulltext.txt", "locator": "Exact primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "673f9c1649ebaea729fb8331f6394dcad15d21b7bea8e6414542210b8e9fdd69", "start_char": 6857, "end_char": 8798, "text_sha256": "09a30283b0d51a099a2687875db729353a5f03f83f616c974d75a284679f1f8f"}
- experimental_model
- Negative-ion electrospray mass spectrometry
- exposure
- 200 µM riboflavin and 400 µM boric acid in WAT solvent at pH 10.3
- limitations
- Nominal mass is consistent with, but does not uniquely establish, the proposed 1:1 structure. No site-resolving NMR or in-vivo binding measurement; signal intensity is not a bound fraction.
- nutrient_topic
- Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
- organism
- Cell-free chemistry
- plain_language
- A laboratory signal suggests boron can attach to vitamin B2; this does not prove that usual boron intake depletes B2.
- primary_references
- [boron-p42012780] Identification of a Riboflavin-Boric Acid Complex by Electrospray Ionization Mass Spectrometry. (2026). https://pubmed.ncbi.nlm.nih.gov/42012780/ DOI: 10.1007/s12011-026-05110-9
- tissue_or_cell_type
- Purified riboflavin in alkaline solvent
Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 183–194
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Negative-ion electrospray mass spectrometry · source_derived_draft · unverified_draft
### boron-riboflavin-adduct An additional m/z 401.3 ion was consistent with a 1:1 riboflavin–boric-acid complex in alkaline electrospray experiments; the ribityl binding site was not resolved. Condition category: normal nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: A laboratory signal suggests boron can attach to vitamin B2; this does not prove that usual boron intake depletes B2. organism: Cell-free chemistry tissue_or_cell_type: Purified riboflavin in alkaline solvent experimental_model: Negative-ion electrospray mass spectrometry limitations: Nominal mass is consistent with, but does not uniquely establish, the proposed 1:1 structure. No site-resolving NMR or in-vivo binding measurement; signal intensity is not a bound fraction. exposure: 200 µM riboflavin and 400 µM boric acid in WAT solvent at pH 10.3 evidence_span: {"source_cache": "artifacts/boron-research/42012780.fulltext.txt", "locator": "Exact primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "673f9c1649ebaea729fb8331f6394dcad15d21b7bea8e6414542210b8e9fdd69", "start_char": 6857, "end_char": 8798, "text_sha256": "09a30283b0d51a099a2687875db729353a5f03f83f616c974d75a284679f1f8f"} [boron-p42012780] Identification of a Riboflavin-Boric Acid Complex by Electrospray Ionization Mass Spectrometry. (2026). https://pubmed.ncbi.nlm.nih.gov/42012780/ DOI: 10.1007/s12011-026-05110-9
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.