Component
Boron complex with NADH
Boron complex with NADH. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
NADH formed a monoester boron adduct in the analyzed solutions, whereas the additional diester and diborate forms observed for NAD+ were not detected for NADH.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/boron-research/12827632.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "a7c91724a5710f61e1907669a1137b421e1e13117ae707e567bd16ca0eea9ed6", "start_char": 0, "end_char": 1255, "text_sha256": "a7c91724a5710f61e1907669a1137b421e1e13117ae707e567bd16ca0eea9ed6"}
- experimental_model
- Electrospray mass spectrometry and boron-11 NMR
- exposure
- NAD+/NADH with boric acid or borate across pH conditions; complexes detected at 50 µM each at pH 7
- limitations
- Chemical structure experiments do not establish cellular concentrations or physiological consequences.
- nutrient_topic
- Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
- organism
- Cell-free chemistry
- plain_language
- Oxidized and reduced NAD do not necessarily make the same boron complexes.
- primary_references
- [boron-p12827632] Esterification of borate with NAD+ and NADH as studied by electrospray ionization mass spectrometry and 11B NMR spectroscopy. (2003). https://pubmed.ncbi.nlm.nih.gov/12827632/ DOI: 10.1002/jms.476
- tissue_or_cell_type
- Purified nucleotide solutions
Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 131–142
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Electrospray mass spectrometry and boron-11 NMR · source_derived_draft · unverified_draft
### boron-nadh-adduct-structure NADH formed a monoester boron adduct in the analyzed solutions, whereas the additional diester and diborate forms observed for NAD+ were not detected for NADH. Condition category: normal nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: Oxidized and reduced NAD do not necessarily make the same boron complexes. organism: Cell-free chemistry tissue_or_cell_type: Purified nucleotide solutions experimental_model: Electrospray mass spectrometry and boron-11 NMR limitations: Chemical structure experiments do not establish cellular concentrations or physiological consequences. exposure: NAD+/NADH with boric acid or borate across pH conditions; complexes detected at 50 µM each at pH 7 evidence_span: {"source_cache": "artifacts/boron-research/12827632.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "a7c91724a5710f61e1907669a1137b421e1e13117ae707e567bd16ca0eea9ed6", "start_char": 0, "end_char": 1255, "text_sha256": "a7c91724a5710f61e1907669a1137b421e1e13117ae707e567bd16ca0eea9ed6"} [boron-p12827632] Esterification of borate with NAD+ and NADH as studied by electrospray ionization mass spectrometry and 11B NMR spectroscopy. (2003). https://pubmed.ncbi.nlm.nih.gov/12827632/ DOI: 10.1002/jms.476
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.