Component
Gut bacterial NADH content
Gut bacterial NADH content. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Berberine reduced bacterial NADH levels in the tested systems.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/berberine-research/28403947.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "cfddc94ff2b2fde20038169c5734cb9d4968c6939ebb94052b9638c8043cc877", "start_char": 0, "end_char": 2151, "text_sha256": "cfddc94ff2b2fde20038169c5734cb9d4968c6939ebb94052b9638c8043cc877"}
- experimental_model
- Bacterial culture and animal route/antibiotic experiments
- exposure
- Oral versus intraperitoneal berberine; antibiotics and direct butyrate comparison
- limitations
- Preclinical evidence. Butyrate production was an indirect microbial route; injected berberine retained separate metabolic effects without raising butyrate. Does not establish probiotic synergy in people.
- nutrient_topic
- Berberine research collection; topical membership is not evidence of a direct dietary effect. · Berberine
- organism
- Gut bacteria and rodents
- plain_language
- The bacterial energy state changed; this is not a measured human vitamin deficiency.
- primary_references
- [berberine-p28403947] Berberine-induced bioactive metabolites of the gut microbiota improve energy metabolism. (2017). https://pubmed.ncbi.nlm.nih.gov/28403947/ DOI: 10.1016/j.metabol.2017.02.003
- tissue_or_cell_type
- Short-chain fatty acid production
Berberine: metabolism, nutrient connections and drug interactions (2026-09-17) · lines 1013–1024
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Bacterial culture and animal route/antibiotic experiments · source_derived_draft · unverified_draft
### berberine-bacterial-nadh Berberine reduced bacterial NADH levels in the tested systems. Condition category: normal nutrient_topic: Berberine research collection; topical membership is not evidence of a direct dietary effect. plain_language: The bacterial energy state changed; this is not a measured human vitamin deficiency. organism: Gut bacteria and rodents tissue_or_cell_type: Short-chain fatty acid production experimental_model: Bacterial culture and animal route/antibiotic experiments limitations: Preclinical evidence. Butyrate production was an indirect microbial route; injected berberine retained separate metabolic effects without raising butyrate. Does not establish probiotic synergy in people. exposure: Oral versus intraperitoneal berberine; antibiotics and direct butyrate comparison evidence_span: {"source_cache": "artifacts/berberine-research/28403947.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "cfddc94ff2b2fde20038169c5734cb9d4968c6939ebb94052b9638c8043cc877", "start_char": 0, "end_char": 2151, "text_sha256": "cfddc94ff2b2fde20038169c5734cb9d4968c6939ebb94052b9638c8043cc877"} [berberine-p28403947] Berberine-induced bioactive metabolites of the gut microbiota improve energy metabolism. (2017). https://pubmed.ncbi.nlm.nih.gov/28403947/ DOI: 10.1016/j.metabol.2017.02.003
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.