Component
Axonal sensorimotor peripheral neuropathy
Axonal sensorimotor peripheral neuropathy. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Neurophysiology showed distal axonal sensorimotor neuropathy; all five tested with somatosensory evoked potentials also had central or proximal pathway abnormalities.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/copper-research/18495738.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "0869f1a2ef3e333451666857ce5f005a08028c0fec6b384dce5fa69b4ae15644", "start_char": 0, "end_char": 1153, "text_sha256": "0869f1a2ef3e333451666857ce5f005a08028c0fec6b384dce5fa69b4ae15644"}
- experimental_model
- Clinical neurophysiology case series
- exposure
- Six patients with copper-deficiency myeloneuropathy
- limitations
- Small case series; does not identify one causal cuproenzyme or establish that B12 deficiency caused the syndrome.
- nutrient_topic
- Copper research collection; topical membership is not evidence of a direct dietary effect. · Copper
- organism
- Human
- plain_language
- The impairment was not limited to one part of the nerve pathway.
- primary_references
- [copper-p18495738] Clinical and electrodiagnostic findings in copper deficiency myeloneuropathy. (2009). https://pubmed.ncbi.nlm.nih.gov/18495738/ DOI: 10.1136/jnnp.2008.144683
- tissue_or_cell_type
- Peripheral and central sensory pathways
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Copper: transport, cuproenzymes, deficiency, excess and nutrient interactions (2026-09-17) · lines 1430–1441
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Clinical neurophysiology case series · source_derived_draft · unverified_draft
### copper-cud-axonal-neuropathy Neurophysiology showed distal axonal sensorimotor neuropathy; all five tested with somatosensory evoked potentials also had central or proximal pathway abnormalities. Condition category: nutrient_deficiency nutrient_topic: Copper research collection; topical membership is not evidence of a direct dietary effect. plain_language: The impairment was not limited to one part of the nerve pathway. organism: Human tissue_or_cell_type: Peripheral and central sensory pathways experimental_model: Clinical neurophysiology case series limitations: Small case series; does not identify one causal cuproenzyme or establish that B12 deficiency caused the syndrome. exposure: Six patients with copper-deficiency myeloneuropathy evidence_span: {"source_cache": "artifacts/copper-research/18495738.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "0869f1a2ef3e333451666857ce5f005a08028c0fec6b384dce5fa69b4ae15644", "start_char": 0, "end_char": 1153, "text_sha256": "0869f1a2ef3e333451666857ce5f005a08028c0fec6b384dce5fa69b4ae15644"} [copper-p18495738] Clinical and electrodiagnostic findings in copper deficiency myeloneuropathy. (2009). https://pubmed.ncbi.nlm.nih.gov/18495738/ DOI: 10.1136/jnnp.2008.144683
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.