Component
Clinician-rated autism trial outcomes
Clinician-rated autism trial outcomes. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Clinician-rated scales improved, whereas caregiver-rated scales did not significantly differ from placebo.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/sulforaphane-research/36427174.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "82957fc566b0bccc87dd6f53d6ad61edfa3d5b0b99ba6f557628c68f53faf1cc", "start_char": 0, "end_char": 826, "text_sha256": "82957fc566b0bccc87dd6f53d6ad61edfa3d5b0b99ba6f557628c68f53faf1cc"}
- experimental_model
- Randomized double-blind multicenter trial
- exposure
- Twelve-week treatment comparison
- limitations
- Rater-dependent results need replication; do not select only the favorable scale.
- nutrient_topic
- Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. · Sulforaphane / SFN, stereochemistry specified per study
- organism
- Human, 108 participants with ASD in China
- plain_language
- The trial did not give one consistent result across observers.
- primary_references
- [sulforaphane-p36427174] Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial. (2024). https://pubmed.ncbi.nlm.nih.gov/36427174/ DOI: 10.1007/s10803-022-05784-9
- tissue_or_cell_type
- Caregiver versus clinician outcome ratings
Sulforaphane: formation, electrophile sensing and nutrient connections (2026-09-17) · lines 1399–1410
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind multicenter trial · source_derived_draft · unverified_draft
### sulforaphane-autism-rater-difference Clinician-rated scales improved, whereas caregiver-rated scales did not significantly differ from placebo. Condition category: normal nutrient_topic: Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. plain_language: The trial did not give one consistent result across observers. organism: Human, 108 participants with ASD in China tissue_or_cell_type: Caregiver versus clinician outcome ratings experimental_model: Randomized double-blind multicenter trial limitations: Rater-dependent results need replication; do not select only the favorable scale. exposure: Twelve-week treatment comparison evidence_span: {"source_cache": "artifacts/sulforaphane-research/36427174.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "82957fc566b0bccc87dd6f53d6ad61edfa3d5b0b99ba6f557628c68f53faf1cc", "start_char": 0, "end_char": 826, "text_sha256": "82957fc566b0bccc87dd6f53d6ad61edfa3d5b0b99ba6f557628c68f53faf1cc"} [sulforaphane-p36427174] Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial. (2024). https://pubmed.ncbi.nlm.nih.gov/36427174/ DOI: 10.1007/s10803-022-05784-9
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.