Component
Adipocyte membrane phosphotyrosine phosphatases (identity unresolved)
Adipocyte membrane phosphotyrosine phosphatases (identity unresolved). Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The isolate increased membrane phosphotyrosine-phosphatase activity in proportion to the amount added, while the isolate itself had no intrinsic phosphatase activity.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/chromium-research/8841143.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "04928cdcbe3e2a282fa43f6a987d1846c6a4e882a6834542b19578b43f8f8322", "start_char": 0, "end_char": 942, "text_sha256": "04928cdcbe3e2a282fa43f6a987d1846c6a4e882a6834542b19578b43f8f8322"}
- experimental_model
- Membrane phosphatase kinetics and inhibitor profiling
- exposure
- Added low-molecular-weight chromium-binding preparation
- limitations
- The phosphatase was not molecularly identified. Inhibitor behavior suggested similarity to PTP1A′ or PTP1B but does not justify assigning this result to a specific gene. Activation here is not proof of universal PTP1B inhibition.
- nutrient_topic
- Chromium research collection; topical membership is not evidence of a direct dietary effect. · Chromium
- organism
- Bovine liver isolate; adipocyte membranes
- plain_language
- This experiment increased a phosphatase activity; the exact enzyme identity remained unresolved.
- primary_references
- [chromium-p8841143] A biologically active form of chromium may activate a membrane phosphotyrosine phosphatase (PTP). (1996). https://pubmed.ncbi.nlm.nih.gov/8841143/ DOI: 10.1021/bi960328y
- tissue_or_cell_type
- Cell-membrane enzyme preparation
Chromium: transport, insulin signaling, nutrient interactions and essentiality debate (2026-09-17) · lines 289–300
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Membrane phosphatase kinetics and inhibitor profiling · source_derived_draft · unverified_draft
### chromium-membrane-phosphatase-activation The isolate increased membrane phosphotyrosine-phosphatase activity in proportion to the amount added, while the isolate itself had no intrinsic phosphatase activity. Condition category: normal nutrient_topic: Chromium research collection; topical membership is not evidence of a direct dietary effect. plain_language: This experiment increased a phosphatase activity; the exact enzyme identity remained unresolved. organism: Bovine liver isolate; adipocyte membranes tissue_or_cell_type: Cell-membrane enzyme preparation experimental_model: Membrane phosphatase kinetics and inhibitor profiling limitations: The phosphatase was not molecularly identified. Inhibitor behavior suggested similarity to PTP1A′ or PTP1B but does not justify assigning this result to a specific gene. Activation here is not proof of universal PTP1B inhibition. exposure: Added low-molecular-weight chromium-binding preparation evidence_span: {"source_cache": "artifacts/chromium-research/8841143.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "04928cdcbe3e2a282fa43f6a987d1846c6a4e882a6834542b19578b43f8f8322", "start_char": 0, "end_char": 942, "text_sha256": "04928cdcbe3e2a282fa43f6a987d1846c6a4e882a6834542b19578b43f8f8322"} [chromium-p8841143] A biologically active form of chromium may activate a membrane phosphotyrosine phosphatase (PTP). (1996). https://pubmed.ncbi.nlm.nih.gov/8841143/ DOI: 10.1021/bi960328y
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.