Component

Stress-induced state anxiety

Independent cellular process record; interpretation is limited by each linked claim and its study context.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

Where it participates (unsigned role)

  1. One week of combined lysine and arginine reduced trait and stress-induced state anxiety in a randomized trial of 108 healthy Japanese adults.

    L-Lysine → Trait and stress-induced state anxiety source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Randomized double-blind placebo-controlled trial; 2.64 g/day of each amino acid
    limitations
    Short duration; no lysine-only arm; no established treatment effect for diagnosed anxiety disorders.
    organism
    Homo sapiens
    plain_language
    The tested mixture improved anxiety scores; the contribution of lysine alone is unknown.
    primary_references
    [smriga2007] Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans (2007). https://pubmed.ncbi.nlm.nih.gov/17510493/ DOI: 10.2220/biomedres.28.85
    tissue_or_cell_type
    Behavioral questionnaires

    L-Lysine: mechanism-first literature curation (2026-09-17) · lines 729–737

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled trial; 2.64 g/day of each amino acid · source_derived_draft · unverified_draft

    ### lysine-arginine-anxiety One week of combined lysine and arginine reduced trait and stress-induced state anxiety in a randomized trial of 108 healthy Japanese adults. Plain language: The tested mixture improved anxiety scores; the contribution of lysine alone is unknown. Condition category: normal organism: Homo sapiens tissue_or_cell_type: Behavioral questionnaires experimental_model: Randomized double-blind placebo-controlled trial; 2.64 g/day of each amino acid limitations: Short duration; no lysine-only arm; no established treatment effect for diagnosed anxiety disorders. [smriga2007] Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans (2007). https://pubmed.ncbi.nlm.nih.gov/17510493/ DOI: 10.2220/biomedres.28.85
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards