Component
Rat Kcnq5 (Kv7.5)
Rat Kcnq5 (Kv7.5). Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
Where it participates (unsigned role)
Rat arterial SMIT1 associated with Kv7.4/Kv7.5 channels in the reported interaction experiments.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/inositol-research/32787517.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5581d37bc8ebfa221d5d351a107a7fa9a76a8b1e7476599e469648779622b3c3", "start_char": 0, "end_char": 1875, "text_sha256": "5581d37bc8ebfa221d5d351a107a7fa9a76a8b1e7476599e469648779622b3c3"}
- experimental_model
- Arterial physiology, protein interactions and knockdown
- exposure
- SMIT1 manipulation, myo-inositol/raffinose and Kv7 blockade
- limitations
- Rat ex vivo arteries; not proof of a blood-pressure benefit from human inositol supplements.
- nutrient_topic
- Inositol research collection; topical membership is not evidence of a direct dietary effect. · Inositol (stereoisomer family)
- organism
- Rattus norvegicus
- plain_language
- An inositol transporter can physically interact with a potassium-channel complex.
- primary_references
- [ino-p32787517] SMIT (Sodium-Myo-Inositol Transporter) 1 Regulates Arterial Contractility Through the Modulation of Vascular Kv7 Channels. (2020). https://pubmed.ncbi.nlm.nih.gov/32787517/ DOI: 10.1161/atvbaha.120.315096
- tissue_or_cell_type
- Renal and mesenteric arteries
Inositol: synthesis, signaling, mineral interactions and conditional deficiency (2026-09-17) · lines 1042–1053
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Arterial physiology, protein interactions and knockdown · source_derived_draft · unverified_draft
### ino-smit1-kv7 Rat arterial SMIT1 associated with Kv7.4/Kv7.5 channels in the reported interaction experiments. Condition category: normal nutrient_topic: Inositol research collection; topical membership is not evidence of a direct dietary effect. plain_language: An inositol transporter can physically interact with a potassium-channel complex. organism: Rattus norvegicus tissue_or_cell_type: Renal and mesenteric arteries experimental_model: Arterial physiology, protein interactions and knockdown limitations: Rat ex vivo arteries; not proof of a blood-pressure benefit from human inositol supplements. exposure: SMIT1 manipulation, myo-inositol/raffinose and Kv7 blockade evidence_span: {"source_cache": "artifacts/inositol-research/32787517.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5581d37bc8ebfa221d5d351a107a7fa9a76a8b1e7476599e469648779622b3c3", "start_char": 0, "end_char": 1875, "text_sha256": "5581d37bc8ebfa221d5d351a107a7fa9a76a8b1e7476599e469648779622b3c3"} [ino-p32787517] SMIT (Sodium-Myo-Inositol Transporter) 1 Regulates Arterial Contractility Through the Modulation of Vascular Kv7 Channels. (2020). https://pubmed.ncbi.nlm.nih.gov/32787517/ DOI: 10.1161/atvbaha.120.315096
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.