Component
Guanosine monophosphate
5-prime GMP, distinct from cyclic GMP.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
Where it participates (unsigned role)
Activated rod phosphodiesterase hydrolyzed cyclic GMP in the phototransduction reconstitution.
Experimental context and source evidence
- experimental_model
- Biochemical phosphodiesterase assay
- limitations
- The channel step was tested in a separate experiment.
- nutrient_topic
- Vitamin A research collection; topical membership is not evidence of a direct dietary effect. · Vitamin A
- organism
- Bos taurus
- plain_language
- cGMP destruction passes the light signal toward channel closure.
- primary_references
- [fung-1981] Flow of information in the light-triggered cyclic nucleotide cascade of vision (1981). https://pubmed.ncbi.nlm.nih.gov/6264430/ DOI: 10.1073/pnas.78.1.152
- tissue_or_cell_type
- Rod outer-segment proteins
Vitamin A: forms, mechanisms, deficiency and excess (2026-09-17) · lines 927–936
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Biochemical phosphodiesterase assay · source_derived_draft · unverified_draft
### a-vision-pde6-cgmp Activated rod phosphodiesterase hydrolyzed cyclic GMP in the phototransduction reconstitution. Condition category: normal nutrient_topic: Vitamin A research collection; topical membership is not evidence of a direct dietary effect. plain_language: cGMP destruction passes the light signal toward channel closure. organism: Bos taurus tissue_or_cell_type: Rod outer-segment proteins experimental_model: Biochemical phosphodiesterase assay limitations: The channel step was tested in a separate experiment. [fung-1981] Flow of information in the light-triggered cyclic nucleotide cascade of vision (1981). https://pubmed.ncbi.nlm.nih.gov/6264430/ DOI: 10.1073/pnas.78.1.152
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.