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Ovine recombinant enzyme.\nexposure: D- and L-ibuprofen and flurbiprofen tested against the mutant panel\nevidence_span: {\"source_cache\": \"artifacts/ibuprofen-research/8567676.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"773dc61cda18ae93ea7dfaf128870c2c5926fb828d7a1563f413e97e29893eda\", \"start_char\": 0, \"end_char\": 2200, \"text_sha256\": \"773dc61cda18ae93ea7dfaf128870c2c5926fb828d7a1563f413e97e29893eda\"}\n[ibu-p8567676] Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1. 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