{"id":"fa8c6a39-e907-5b52-8fcf-a25c52f4fd37","stable_key":"d17caac5-7018-5ca8-9e96-95afeb384bc4:pectin-diarrhea-trial","predicate":"increases","statement":"Recovery in the pectin group was 59% versus 15% control on day three and 82% versus 23% on day four.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"71fafb8a-1442-5d55-8e01-ab5325f87c10","mechanism_event_label":"This supervised dietary trial found faster recovery in the pectin group.","subject":{"id":"5449346d-7614-5c4b-bbd2-03fb4dd71aeb","slug":"pectin","display_name":"Pectin, structurally heterogeneous plant polysaccharides","entity_type_key":"chemical_species"},"object":{"id":"b6dd94a1-c1dd-58b9-904c-1c84fa1a6496","slug":"persistent-diarrhea-recovery","display_name":"Recovery from persistent diarrhea in the specified pediatric trial","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"71fafb8a-1442-5d55-8e01-ab5325f87c10","stable_key":"d17caac5-7018-5ca8-9e96-95afeb384bc4:pectin-diarrhea-trial-event","event_type":"observed_intervention","label":"This supervised dietary trial found faster recovery in the pectin group.","description":"Recovery in the pectin group was 59% versus 15% control on day three and 82% versus 23% on day four.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5449346d-7614-5c4b-bbd2-03fb4dd71aeb","slug":"pectin","display_name":"Pectin, structurally heterogeneous plant polysaccharides","entity_type_key":"chemical_species"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"b6dd94a1-c1dd-58b9-904c-1c84fa1a6496","slug":"persistent-diarrhea-recovery","display_name":"Recovery from persistent diarrhea in the specified pediatric trial","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_span","value_text":"{\"source_cache\": \"artifacts/pectin-research/11522739.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"955d993768cd772b8a0a137cc97e04a6e83d892f7dd430ce38b27063841b83b2\", \"start_char\": 0, \"end_char\": 1414, \"text_sha256\": \"955d993768cd772b8a0a137cc97e04a6e83d892f7dd430ce38b27063841b83b2\"}","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Randomized double-blind dietary trial in hospitalized infants","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"62 total: pectin19, cooked banana22, rice-control21; seven-day diets; abstract reports pectin 4 g/kg","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Historical supervised treatment context with rehydration available. 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(2001). https://pubmed.ncbi.nlm.nih.gov/11522739/ DOI: 10.1053/gast.2001.27178","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Persistent diarrhea; boys aged 5-12 months","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"f2e5597b-2c12-55c2-8779-6a7ecd1a7908","evidence_kind":"source_excerpt","locator":"Lines 1127-1138","start_line":1127,"end_line":1138,"excerpt":"### pectin-diarrhea-trial\nRecovery in the pectin group was 59% versus 15% control on day three and 82% versus 23% on day four.\nCondition category: normal\nnutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: This supervised dietary trial found faster recovery in the pectin group.\norganism: Homo sapiens\ntissue_or_cell_type: Persistent diarrhea; boys aged 5-12 months\nexperimental_model: Randomized double-blind dietary trial in hospitalized infants\nlimitations: Historical supervised treatment context with rehydration available. Not an instruction for infant self-treatment, an ORS replacement or proof of a particular molecular mechanism.\nexposure: 62 total: pectin19, cooked banana22, rice-control21; seven-day diets; abstract reports pectin 4 g/kg\nevidence_span: {\"source_cache\": \"artifacts/pectin-research/11522739.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"955d993768cd772b8a0a137cc97e04a6e83d892f7dd430ce38b27063841b83b2\", \"start_char\": 0, \"end_char\": 1414, \"text_sha256\": \"955d993768cd772b8a0a137cc97e04a6e83d892f7dd430ce38b27063841b83b2\"}\n[pectin-p11522739] Clinical studies in persistent diarrhea: dietary management with green banana or pectin in Bangladeshi children. 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