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Small sample and multiple endpoints.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Chromium research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"chromium","display_name":"Chromium","entity_type_key":"nutrient_element"}},{"dimension":"organism","value_text":"Human with metabolic syndrome","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"An inflammation marker changed even though the main metabolic measures did not.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[chromium-p29773176] Effects of zinc, magnesium, and chromium supplementation on cardiometabolic risk in adults with metabolic syndrome: A double-blind, placebo-controlled randomised trial. (2018). https://pubmed.ncbi.nlm.nih.gov/29773176/ DOI: 10.1016/j.jtemb.2018.03.022","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Metabolic-risk endpoints and CRP","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"ba37c45e-6c38-59b1-84c5-e9e546a4da2d","evidence_kind":"source_excerpt","locator":"Lines 640-651","start_line":640,"end_line":651,"excerpt":"### chromium-triple-mineral-crp\nThe three-mineral regimen reduced serum CRP relative to placebo despite the lack of improvement in the measured metabolic-risk components.\nCondition category: normal\nnutrient_topic: Chromium research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: An inflammation marker changed even though the main metabolic measures did not.\norganism: Human with metabolic syndrome\ntissue_or_cell_type: Metabolic-risk endpoints and CRP\nexperimental_model: Double-blind randomized placebo-controlled trial; 32 adults\nlimitations: Only the three-mineral combination was tested; individual effects and synergy cannot be separated. Small sample and multiple endpoints.\nexposure: 24 weeks: 300 mg magnesium, 600 µg chromium and 36 mg zinc daily versus placebo\nevidence_span: {\"source_cache\": \"artifacts/chromium-research/29773176.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"6107419f3b2f125a5a9971f56f24c1bd454a97512ef432f154c79d26b85c1067\", \"start_char\": 0, \"end_char\": 1208, \"text_sha256\": \"6107419f3b2f125a5a9971f56f24c1bd454a97512ef432f154c79d26b85c1067\"}\n[chromium-p29773176] Effects of zinc, magnesium, and chromium supplementation on cardiometabolic risk in adults with metabolic syndrome: A double-blind, placebo-controlled randomised trial. 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