{"id":"f4cd916b-bcf3-57e7-91f8-7c5369c673d6","stable_key":"cab605fe-8a82-5191-9966-d19a9628c24c:betalains-betanin-identity","predicate":"is_glucoside_of","statement":"Betanin is the 5-O-beta-glucoside of betanidin.","claim_class":"identity","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"470309e8-5c1b-5c03-ab33-7d443ce860e1","mechanism_event_label":"Betanin is the 5-O-beta-glucoside of betanidin.","subject":{"id":"6c12bb61-c9c2-5c6d-a087-a292145ccaf0","slug":"betanin","display_name":"Betanin","entity_type_key":"small_molecule"},"object":{"id":"0ecc49d8-5e91-5a47-9869-6199477c91f0","slug":"betanidin","display_name":"Betanidin","entity_type_key":"small_molecule"},"evidence_count":1,"mechanism_event":{"id":"470309e8-5c1b-5c03-ab33-7d443ce860e1","stable_key":"cab605fe-8a82-5191-9966-d19a9628c24c:betalains-betanin-identity-event","event_type":"observed_relationship","label":"Betanin is the 5-O-beta-glucoside of betanidin.","description":"Betanin is the 5-O-beta-glucoside of betanidin.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"6c12bb61-c9c2-5c6d-a087-a292145ccaf0","slug":"betanin","display_name":"Betanin","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"0ecc49d8-5e91-5a47-9869-6199477c91f0","slug":"betanidin","display_name":"Betanidin","entity_type_key":"small_molecule"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"dose","value_text":"Assay-specific submicromolar to micromolar concentrations; oral arm 300 mL beet juice with 120 mg betanin","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"duration","value_text":"Kinetic assays; urine collected 2-4 h after ingestion","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"Primary PubMed abstract; detailed exposure for PMID 23931157 additionally checked in publisher results. No uninspected full text is claimed.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_scope","value_text":"literature_reviewed; source-derived curation, not universally established human effects","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Cell-free biochemical systems and four human volunteers","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Chemical activity does not establish clinical efficacy or a dietary iron interaction. Identity only; not a demonstrated human conversion rate.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Betalains collection; each molecular form, species, exposure and preparation remains explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"betalains","display_name":"Betalains","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Cell-free biochemical systems and four human volunteers","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Betanin is the 5-O-beta-glucoside of betanidin.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Betalains--a new class of dietary cationized antioxidants. (2001). https://pubmed.ncbi.nlm.nih.gov/11714300/ DOI: 10.1021/jf010456f","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"route","value_text":"In vitro addition; separate oral juice arm","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue","value_text":"Lipid emulsions, membranes, LDL; urine arm separate","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"7c5cc0a2-b963-5f7d-ba95-eeda95c00081","evidence_kind":"source_excerpt","locator":"Lines 17-25","start_line":17,"end_line":25,"excerpt":"## betalains-betanin-identity\nBetanin is the 5-O-beta-glucoside of betanidin.\nModel/species: Cell-free biochemical systems and four human volunteers\nTissue: Lipid emulsions, membranes, LDL; urine arm separate\nExposure: Assay-specific submicromolar to micromolar concentrations; oral arm 300 mL beet juice with 120 mg betanin\nRoute: In vitro addition; separate oral juice arm\nDuration: Kinetic assays; urine collected 2-4 h after ingestion\nLimits: Chemical activity does not establish clinical efficacy or a dietary iron interaction. Identity only; not a demonstrated human conversion rate.\nPrimary reference: Betalains--a new class of dietary cationized antioxidants. (2001). https://pubmed.ncbi.nlm.nih.gov/11714300/ DOI: 10.1021/jf010456f","model_system":"Cell-free biochemical systems and four human volunteers","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Exact archived curation span; an original paraphrase with an individually identified primary reference.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"be94d093-444c-5729-8831-bc33b0ef2fd7","stable_key":"import-cab605fe-8a82-5191-9966-d19a9628c24c","title":"Betalains: mechanisms, molecular forms and cross-actor connections (2026-09-20)","document_type":"imported_text","citation_label":"Original AI-assisted curation of twelve primary research papers; study-specific PubMed/DOI links and limitations retained. Not publisher full text.","file_path":"","sha256":"adb4fb8586481a69da5d2fe5cf62ad1dae2509af524352673fc7427123eeda87","revision_id":"a328b3f9-66d2-59e2-bd8f-de651c3c7649","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}