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(2025). https://pubmed.ncbi.nlm.nih.gov/39929977/ DOI: 10.1038/s41564-025-01932-w","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Fasting glucose and serum exposure","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"e1503f26-5dea-5049-8aab-50e13119f622","evidence_kind":"source_excerpt","locator":"Lines 1178-1189","start_line":1178,"end_line":1189,"excerpt":"### sulforaphane-prediabetes-primary\nThe mean glucose reduction versus placebo was 0.2 mmol/L (95% CI -0.44 to -0.01; P=0.04), below the prespecified 0.3 mmol/L target.\nCondition category: normal\nnutrient_topic: Sulforaphane research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A small statistical signal did not meet the trial's planned target.\norganism: Human prediabetes; 35 extract and 39 placebo participants analyzed\ntissue_or_cell_type: Fasting glucose and serum exposure\nexperimental_model: Randomized double-blind placebo-controlled trial with exploratory microbiome analysis\nlimitations: Primary target was 0.3 mmol/L; subgroup and microbiome results were exploratory and need confirmation.\nexposure: Daily broccoli sprout extract for 12 weeks\nevidence_span: {\"source_cache\": \"artifacts/sulforaphane-research/39929977.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92\", \"start_char\": 0, \"end_char\": 1849, \"text_sha256\": \"525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92\"}\n[sulforaphane-p39929977] Effect of broccoli sprout extract and baseline gut microbiota on fasting blood glucose in prediabetes: a randomized, placebo-controlled trial. 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