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Tea preparation was specific to this experiment.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"L-Theanine research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"theanine","display_name":"L-Theanine","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Twelve healthy humans; dose-ranging subset of three","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Its breakdown products have identities separate from the ingested molecule.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[theanine-p23096008] Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea. (2012). https://pubmed.ncbi.nlm.nih.gov/23096008/ DOI: 10.3945/jn.112.166371","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma, erythrocytes and urine","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"252491d4-dd2c-5b41-856e-59bd44cd5233","evidence_kind":"source_excerpt","locator":"Lines 133-144","start_line":133,"end_line":144,"excerpt":"### theanine-human-glutamate\nPlasma glutamate increased after theanine ingestion, consistent with hydrolysis of the parent compound.\nCondition category: normal\nnutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Its breakdown products have identities separate from the ingested molecule.\norganism: Twelve healthy humans; dose-ranging subset of three\ntissue_or_cell_type: Plasma, erythrocytes and urine\nexperimental_model: Randomized crossover absorption and metabolite study\nlimitations: Small acute study; plasma concentration does not identify brain concentration or clinical response. Tea preparation was specific to this experiment.\nexposure: 100 mg theanine as capsule or green tea; subset 50 and 200 mg\nevidence_span: {\"source_cache\": \"artifacts/theanine-research/23096008.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"0080959c2621f814538b812413bd295d2fdab96bc401c2ed1876fc2e1044406a\", \"start_char\": 0, \"end_char\": 1696, \"text_sha256\": \"0080959c2621f814538b812413bd295d2fdab96bc401c2ed1876fc2e1044406a\"}\n[theanine-p23096008] Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea. (2012). https://pubmed.ncbi.nlm.nih.gov/23096008/ DOI: 10.3945/jn.112.166371","model_system":"Randomized crossover absorption and metabolite study","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [theanine-p23096008] Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea. (2012). https://pubmed.ncbi.nlm.nih.gov/23096008/ DOI: 10.3945/jn.112.166371","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"e2bf3fc8-fc9a-5d50-937a-559a76f8be7d","stable_key":"import-8f12ba85-1a92-5337-a9c0-9cee9b3be90d","title":"L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text.","file_path":"","sha256":"c78f2a1961da546cd8d3ae9131a16613aed0d1032904ca19175b0641647142c1","revision_id":"4ec64995-1e5b-5279-9102-f203cb2e29e5","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}