{"id":"ec6c9f06-0a6f-5cba-9267-ab89f52847d2","stable_key":"561b2b40-5b59-548f-a749-f357f7e2304c:monosodium-glutamate-carbohydrate-emptying-null","predicate":"does_not_change_tested","statement":"The same study found no significant MSG effect for carbohydrate-rich liquid or water meals in nine men.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"32d05bcb-5d39-5553-ac99-1f75e41a4813","mechanism_event_label":"The positive protein-meal result did not generalize to all liquids.","subject":{"id":"2952387b-d69b-5530-a976-a875ad008226","slug":"monosodium-glutamate","display_name":"Monosodium L-glutamate","entity_type_key":"small_molecule"},"object":{"id":"b22afa38-3966-5a96-ba89-f5d3988dbc24","slug":"human-msg-carbohydrate-water-emptying","display_name":"Human carbohydrate/water meal emptying with MSG","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"32d05bcb-5d39-5553-ac99-1f75e41a4813","stable_key":"561b2b40-5b59-548f-a749-f357f7e2304c:monosodium-glutamate-carbohydrate-emptying-null-event","event_type":"observed_relationship","label":"The positive protein-meal result did not generalize to all liquids.","description":"The same study found no significant MSG effect for carbohydrate-rich liquid or water meals in nine men.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"2952387b-d69b-5530-a976-a875ad008226","slug":"monosodium-glutamate","display_name":"Monosodium L-glutamate","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"b22afa38-3966-5a96-ba89-f5d3988dbc24","slug":"human-msg-carbohydrate-water-emptying","display_name":"Human carbohydrate/water meal emptying with MSG","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"7da684a4-2641-5bc6-93ae-8c6aa384e487","slug":"glutamate","display_name":"L-Glutamate","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Within-study meal comparisons.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Not a contradiction caused by different chemical identities.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Monosodium Glutamate (MSG) collection; species, compartment, exposure, co-substrates and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"monosodium-glutamate","display_name":"Monosodium L-glutamate","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"The positive protein-meal result did not generalize to all liquids.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Monosodium L-glutamate added to a high-energy, high-protein liquid diet promotes gastric emptying. · 2009 · https://pubmed.ncbi.nlm.nih.gov/19056566/ · DOI 10.3945/ajcn.2008.26180","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"4a4f421a-5036-533f-ac3e-897592a92a7b","evidence_kind":"source_excerpt","locator":"Lines 226-232","start_line":226,"end_line":232,"excerpt":"## monosodium-glutamate-carbohydrate-emptying-null\nThe positive protein-meal result did not generalize to all liquids.\nThe same study found no significant MSG effect for carbohydrate-rich liquid or water meals in nine men.\nModel: Within-study meal comparisons.\nLimitations: Not a contradiction caused by different chemical identities.\nEvidence access: Primary abstract\nMonosodium L-glutamate added to a high-energy, high-protein liquid diet promotes gastric emptying. · 2009 · https://pubmed.ncbi.nlm.nih.gov/19056566/ · DOI 10.3945/ajcn.2008.26180","model_system":"Within-study meal comparisons.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; evidence access and experimental limitations specified.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"90a81fe5-8622-52f6-b4db-04899206c2b0","stable_key":"import-561b2b40-5b59-548f-a749-f357f7e2304c","title":"Monosodium Glutamate (MSG): taste, gut sensing, exposure and cross-nutrient mechanisms (2026-09-20)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary references, access levels and experimental limitations individually identified. 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