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(1997). https://pubmed.ncbi.nlm.nih.gov/9278568/ DOI: 10.1093/jn/127.9.1833","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Serum carotenoid AUC over 24 hours","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"6bc83c96-8efa-5762-ae5c-2d1e09663d88","evidence_kind":"source_excerpt","locator":"Lines 793-804","start_line":793,"end_line":804,"excerpt":"### lycopene-beta-carotene-response-null\nThe beta-carotene serum AUC did not differ when beta-carotene was taken alone or with lycopene.\nCondition category: normal\nnutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The measured interaction was not symmetrical.\norganism: Human, ten healthy men\ntissue_or_cell_type: Serum carotenoid AUC over 24 hours\nexperimental_model: Randomized-order double-blind crossover dosing experiment\nlimitations: Acute high-dose study; does not justify routine co-supplementation or establish universal competition rules.\nexposure: 60 mg beta-carotene, 60 mg lycopene, or 60 mg of each together\nevidence_span: {\"source_cache\": \"artifacts/lycopene-research/9278568.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"e318f6fef0bfed88403fa2adf46f9713ebddfe6ea586c29614e820442c57d056\", \"start_char\": 0, \"end_char\": 1510, \"text_sha256\": \"e318f6fef0bfed88403fa2adf46f9713ebddfe6ea586c29614e820442c57d056\"}\n[lycopene-p9278568] Ingestion by men of a combined dose of beta-carotene and lycopene does not affect the absorption of beta-carotene but improves that of lycopene. 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