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(2023). https://pubmed.ncbi.nlm.nih.gov/37585292/ DOI: 10.1016/j.celrep.2023.112982","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"intact eye; rod photoreceptors","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"machinery_impairment","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"c64aca0a-b33b-5eed-b67a-4aac55f18058","evidence_kind":"source_excerpt","locator":"Lines 543-556","start_line":543,"end_line":556,"excerpt":"### vae-rgr-loss-rod-dark-adaptation\nRgrStop/Stop mice with intact Gnat1 recovered rod ERG responses more slowly after sustained bright illumination than Rgr-intact controls.\nCondition category: machinery_impairment\nnutrient_topic: Vitamin A expansion research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: The light-driven recycling route also helped rods recover after the light was switched off.\norganism: Mus musculus\ntissue_or_cell_type: intact eye; rod photoreceptors\nexperimental_model: Transcriptional-stop Rgr knockout; rod-driven ERG\nlimitations: Post-illumination recovery does not imply RGR catalyzes isomerization in darkness.\nexposure: 530-nm background at 300 cd/m2 for 30 minutes; recovery followed in darkness.\ncross_nutrient: false\nevidence_location: Figure 8A; Results: RGR supports rod dark adaptation\nnutrient: Vitamin A\n[vav-tworak2023] Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. (2023). https://pubmed.ncbi.nlm.nih.gov/37585292/ DOI: 10.1016/j.celrep.2023.112982","model_system":"Transcriptional-stop Rgr knockout; rod-driven ERG","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [vav-tworak2023] Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. (2023). https://pubmed.ncbi.nlm.nih.gov/37585292/ DOI: 10.1016/j.celrep.2023.112982","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"83131a07-353f-5301-9ce6-50754c194952","stable_key":"import-3c852f36-7951-5fd9-9013-d771a8d16d8a","title":"Vitamin A expansion: reproduction, light-driven vision and shared mechanisms (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. 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