{"id":"dacdea6c-6eec-59c7-a0ac-0deefd3d980b","stable_key":"59b18080-c560-563d-abc5-bac4ee82a27c:ergothioneine-cv-observational","predicate":"associated_with_lower","statement":"In 3236 initially CVD- and diabetes-free participants, higher baseline ergothioneine predicted lower coronary disease and mortality over a median 21.4 years.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"negative","is_public":true,"mechanism_event_id":"7a18bfd8-a974-50ce-beca-4778ecbaa4f8","mechanism_event_label":"A higher blood marker tracked better long-term outcomes.","subject":{"id":"953f6383-3113-5db3-8a49-e424f86e7380","slug":"human-blood-ergothioneine","display_name":"Human blood ergothioneine concentration, compartment specified","entity_type_key":"cellular_process"},"object":{"id":"e02bd1d0-9f95-595c-b8a3-525b1a7b1fdf","slug":"human-ergo-cardiovascular-mortality-risk","display_name":"Human cardiovascular/mortality association with baseline ergothioneine","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"7a18bfd8-a974-50ce-beca-4778ecbaa4f8","stable_key":"59b18080-c560-563d-abc5-bac4ee82a27c:ergothioneine-cv-observational-event","event_type":"observed_relationship","label":"A higher blood marker tracked better long-term outcomes.","description":"In 3236 initially CVD- and diabetes-free participants, higher baseline ergothioneine predicted lower coronary disease and mortality over a median 21.4 years.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"953f6383-3113-5db3-8a49-e424f86e7380","slug":"human-blood-ergothioneine","display_name":"Human blood ergothioneine concentration, compartment specified","entity_type_key":"cellular_process"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"e02bd1d0-9f95-595c-b8a3-525b1a7b1fdf","slug":"human-ergo-cardiovascular-mortality-risk","display_name":"Human cardiovascular/mortality association with baseline ergothioneine","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"939c92c3-50ea-5a4a-9654-8e3b94448132","slug":"ergothioneine","display_name":"L-Ergothioneine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"biomarker_context","comparator":null,"unit":null,"notes":"Imported condition classification; 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