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(2008). https://pubmed.ncbi.nlm.nih.gov/18511687/ DOI: 10.1126/science.1157643","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Cytosol","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"0a42dbd3-02eb-58a3-a7ea-289eb4b762ba","evidence_kind":"source_excerpt","locator":"Lines 589-600","start_line":589,"end_line":600,"excerpt":"### iron-pcbp-loads-ferritin\nPCBP1 bound iron and ferritin and facilitated iron loading into ferritin in vitro and in cellular systems.\nCondition category: normal\nnutrient_topic: Iron research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Iron has a delivery protein for safe storage, rather than simply drifting into every target.\norganism: Human PCBP1 and ferritin in yeast and human cells\ntissue_or_cell_type: Cytosol\nexperimental_model: Yeast expression, in-vitro binding/loading and human-cell depletion\nlimitations: Chaperone-mediated distribution is distinct from total cellular iron.\nexposure: PCBP1 expression and depletion\nevidence_span: {\"source_cache\": \"artifacts/iron-research/18511687.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"d8000e5c5f59dc72e9697d5aac77ce5070a1c92f6cada7e863088ec917684c68\", \"start_char\": 0, \"end_char\": 703, \"text_sha256\": \"d8000e5c5f59dc72e9697d5aac77ce5070a1c92f6cada7e863088ec917684c68\"}\n[iron-p18511687] A cytosolic iron chaperone that delivers iron to ferritin. 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