{"id":"d1698ea2-26a3-5879-a04d-d7a468925c43","stable_key":"c3df3634-4c3a-5099-a5d9-e4f6344c1084:fortification-child-growth","predicate":"fortification_associated_with_greater","statement":"In the Pakistani wheat-fortification trial, children receiving lysine-fortified flour gained more height and weight than controls over three months.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"2efd2061-44a4-5a59-b021-280564c44b9c","mechanism_event_label":"Improving a lysine-poor staple was associated with better child growth in this dietary setting.","subject":{"id":"5fff6664-209e-5c35-b88e-ac15c1c5fbc0","slug":"l-lysine","display_name":"L-Lysine","entity_type_key":"small_molecule"},"object":{"id":"e4138b53-d4ba-5d29-84df-0dd888198a96","slug":"child-growth","display_name":"Child height and weight gain","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"2efd2061-44a4-5a59-b021-280564c44b9c","stable_key":"c3df3634-4c3a-5099-a5d9-e4f6344c1084:fortification-child-growth-event","event_type":"observed_intervention","label":"Improving a lysine-poor staple was associated with better child growth in this dietary setting.","description":"In the Pakistani wheat-fortification trial, children receiving lysine-fortified flour gained more height and weight than controls over three months.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5fff6664-209e-5c35-b88e-ac15c1c5fbc0","slug":"l-lysine","display_name":"L-Lysine","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"e4138b53-d4ba-5d29-84df-0dd888198a96","slug":"child-growth","display_name":"Child height and weight gain","entity_type_key":"cellular_process"},"role":"object","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"bdf36a55-5e3f-517a-b4d1-1cfc4ebab4b5","slug":"child-height-gain","display_name":"Child height gain","entity_type_key":"cellular_process"},"role":"increased_outcome","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"53599c60-06c5-5d06-a6ee-8372064d1323","slug":"child-weight-gain","display_name":"Child weight gain","entity_type_key":"cellular_process"},"role":"increased_outcome","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"nutrient_deficiency","comparator":null,"unit":null,"notes":"Imported condition classification; 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Original study references: [hussain2004] Lysine fortification of wheat flour improves selected indices of the nutritional status of predominantly cereal-eating families in Pakistan (2004). https://pubmed.ncbi.nlm.nih.gov/15214256/ DOI: 10.1177/156482650402500202","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"7633bde7-dcc9-5086-91c6-a45eb96857f3","stable_key":"import-c3df3634-4c3a-5099-a5d9-e4f6344c1084","title":"L-Lysine: mechanism-first literature curation (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text.","file_path":"","sha256":"93998d47c21525409ba82f1c82ededf2893dff15fbe61c7deffc175b0e298e97","revision_id":"3897e31f-6624-59e1-a053-8a81b7361632","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}