{"id":"ce182854-b848-554e-a35a-49b771d4f023","stable_key":"c836a883-ac18-5eb2-9971-2f0b542feba8:blackgarlic-urine","predicate":"reported_relationship","statement":"Thirty-three organosulfur analytes were characterized in urine after twenty grams of black garlic, including N-acetyl products.","claim_class":"observational","status":"source_recorded","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"d25e2ee6-6bd6-5438-abf5-b179eaf64e99","mechanism_event_label":"Thirty-three organosulfur analytes were characterized in urine after twenty grams of black garlic, including N-acetyl products.","subject":{"id":"44d0be70-b60b-50db-b07b-de731a5110e6","slug":"black-garlic-moreno-2023","display_name":"Black garlic meal in the 2023 urine study","entity_type_key":"botanical"},"object":{"id":"d162eeac-d58e-55a1-b2bf-222164823823","slug":"human-black-garlic-urinary-organosulfur","display_name":"Urinary organosulfur analytes after human black-garlic intake","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"d25e2ee6-6bd6-5438-abf5-b179eaf64e99","stable_key":"c836a883-ac18-5eb2-9971-2f0b542feba8:blackgarlic-urine-event","event_type":"experimental_observation","label":"Thirty-three organosulfur analytes were characterized in urine after twenty grams of black garlic, including N-acetyl products.","description":"**Black garlic is a separate intervention.** After twenty grams of black garlic, a human urine study characterized thirty-three organosulfur analytes over twenty-four hours, including SAC-related and alliin-related N-acetyl products. Urinary detection supports exposure to constituents of that preparation; it is not evidence that intact allicin reached a tumor, artery, or brain. Some pathway assignments were tentative. [Moreno-Ortega 2023](https://pmc.ncbi.nlm.nih.gov/articles/PMC10135770/)","status":"provisional","compartment":null,"participants":[{"entity":{"id":"44d0be70-b60b-50db-b07b-de731a5110e6","slug":"black-garlic-moreno-2023","display_name":"Black garlic meal in the 2023 urine study","entity_type_key":"botanical"},"role":"tested factor","stoichiometry":null,"state_label":"as reported","sequence_order":0,"notes":""},{"entity":{"id":"d162eeac-d58e-55a1-b2bf-222164823823","slug":"human-black-garlic-urinary-organosulfur","display_name":"Urinary organosulfur analytes after human black-garlic intake","entity_type_key":"cellular_process"},"role":"measured outcome","stoichiometry":null,"state_label":"not_reported","sequence_order":1,"notes":""},{"entity":{"id":"8c2c295d-68b3-5e62-b1a7-00fcf915e3cc","slug":"s-allylcysteine","display_name":"S-allyl-L-cysteine / SAC","entity_type_key":"small_molecule"},"role":"preparation-related precursor","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"0837bab7-ef2d-533f-9025-740a1c76cdf3","slug":"n-acetyl-s-allylcysteine","display_name":"N-acetyl-S-allyl-L-cysteine","entity_type_key":"small_molecule"},"role":"detected metabolite","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""},{"entity":{"id":"f592645c-77f9-59af-b241-96fc60d07b94","slug":"n-acetyl-s-allylcysteine-sulfoxide","display_name":"N-acetyl-S-allyl-L-cysteine sulfoxide","entity_type_key":"small_molecule"},"role":"detected metabolite","stoichiometry":null,"state_label":"","sequence_order":4,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary full text available; selected claim-relevant methods, results, tables/figures and limitations reviewed. Supplemental proteome and all secondary findings are not exhaustively extracted.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Healthy-human acute feeding, 24-hour urine; UHPLC-HRMS.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"interpretation_status","value_text":"Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Some pathway assignments tentative; not proof of systemic intact allicin or exact pathway flux.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Thirty-three organosulfur analytes were characterized in urine after twenty grams of black garlic, including N-acetyl products.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Bioavailability of Organosulfur Compounds after the Ingestion of Black Garlic by Healthy Humans. | 2023 | DOI 10.3390/antiox12040925 | PMID 37107300 | https://pubmed.ncbi.nlm.nih.gov/37107300/ | https://pmc.ncbi.nlm.nih.gov/articles/PMC10135770/ | https://doi.org/10.3390/antiox12040925","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"source_locator","value_text":"Reviewed reference lines 33-33; exact primary location described in quoted passage where extracted.","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"d72f3b7d-ab1e-5ead-9043-919e5c675ce7","evidence_kind":"source_excerpt","locator":"Lines 33-33","start_line":33,"end_line":33,"excerpt":"**Black garlic is a separate intervention.** After twenty grams of black garlic, a human urine study characterized thirty-three organosulfur analytes over twenty-four hours, including SAC-related and alliin-related N-acetyl products. Urinary detection supports exposure to constituents of that preparation; it is not evidence that intact allicin reached a tumor, artery, or brain. Some pathway assignments were tentative. [Moreno-Ortega 2023](https://pmc.ncbi.nlm.nih.gov/articles/PMC10135770/)","model_system":"Healthy-human acute feeding, 24-hour urine; UHPLC-HRMS.","directness":"reported_statement","verification_status":"source_recorded","notes":"Exact excerpt of the retained AI-assisted reviewed reference; primary sources are cited in primary_references and access scope is retained. Not a verbatim quotation from a primary paper.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"10820a6b-594a-547d-97f9-906ab4cc1d6e","stable_key":"import-c836a883-ac18-5eb2-9971-2f0b542feba8","title":"Allicin: detailed mechanisms of action (reviewed 5 October 2026)","document_type":"imported_text","citation_label":"Original AI-assisted review of primary studies and, where relevant, official regulatory records. 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