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Zinc was given intrahippocampally at a defined dose rather than altered nutritionally.\nexposure: Zinc with the synthetic neurosteroid ganaxolone, applied to neurons and intrahippocampally in fully kindled mice\nevidence_span: {\"source_cache\": \"artifacts/gaba-research/30471294.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"657923c781b7e3a3309235bce60303fde53f18d7a830cde050b268269f02747a\", \"start_char\": 0, \"end_char\": 1814, \"text_sha256\": \"657923c781b7e3a3309235bce60303fde53f18d7a830cde050b268269f02747a\"}\n[gb-p30471294] Zinc reduces antiseizure activity of neurosteroids by selective blockade of extrasynaptic GABA-A receptor-mediated tonic inhibition in the hippocampus. 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