{"id":"c568e661-6761-5991-b4b7-df22322acdf5","stable_key":"8f12ba85-1a92-5337-a9c0-9cee9b3be90d:theanine-adhd-latency-null","predicate":"did_not_change","statement":"Sleep latency was unchanged in the boys-with-ADHD trial.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"3f3f013e-3bab-5d97-a57e-5a7c90d65098","mechanism_event_label":"Different sleep outcomes need separate entries.","subject":{"id":"33a051c5-dba8-53cd-8761-c53732c447e6","slug":"theanine","display_name":"L-Theanine","entity_type_key":"small_molecule"},"object":{"id":"36b9edba-2a63-5172-ab86-5c4e2b7ab081","slug":"sleep-latency","display_name":"Sleep latency, measurement specified by study","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"3f3f013e-3bab-5d97-a57e-5a7c90d65098","stable_key":"8f12ba85-1a92-5337-a9c0-9cee9b3be90d:theanine-adhd-latency-null-event","event_type":"observed_intervention","label":"Different sleep outcomes need separate entries.","description":"Sleep latency was unchanged in the boys-with-ADHD trial.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"33a051c5-dba8-53cd-8761-c53732c447e6","slug":"theanine","display_name":"L-Theanine","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"36b9edba-2a63-5172-ab86-5c4e2b7ab081","slug":"sleep-latency","display_name":"Sleep latency, measurement specified by study","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_span","value_text":"{\"source_cache\": \"artifacts/theanine-research/22214254.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c4233ab5e7f87272614c99ebced46c55f732b71dc105c6e7adc56e433be57871\", \"start_char\": 0, \"end_char\": 2347, \"text_sha256\": \"c4233ab5e7f87272614c99ebced46c55f732b71dc105c6e7adc56e433be57871\"}","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Randomized double-blind placebo-controlled actigraphy trial","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"400 mg/day for six weeks; stimulant treatment stratified","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Short pediatric study in a specific population. Does not establish treatment of ADHD core symptoms or a general pediatric recommendation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"L-Theanine research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"theanine","display_name":"L-Theanine","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"98 boys aged 8-12 with ADHD","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Different sleep outcomes need separate entries.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[theanine-p22214254] The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. (2011). https://pubmed.ncbi.nlm.nih.gov/22214254/","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Objective sleep monitoring","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"a9352606-4e78-5309-ab1f-ff59edf8ada3","evidence_kind":"source_excerpt","locator":"Lines 1173-1184","start_line":1173,"end_line":1184,"excerpt":"### theanine-adhd-latency-null\nSleep latency was unchanged in the boys-with-ADHD trial.\nCondition category: normal\nnutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Different sleep outcomes need separate entries.\norganism: 98 boys aged 8-12 with ADHD\ntissue_or_cell_type: Objective sleep monitoring\nexperimental_model: Randomized double-blind placebo-controlled actigraphy trial\nlimitations: Short pediatric study in a specific population. Does not establish treatment of ADHD core symptoms or a general pediatric recommendation.\nexposure: 400 mg/day for six weeks; stimulant treatment stratified\nevidence_span: {\"source_cache\": \"artifacts/theanine-research/22214254.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c4233ab5e7f87272614c99ebced46c55f732b71dc105c6e7adc56e433be57871\", \"start_char\": 0, \"end_char\": 2347, \"text_sha256\": \"c4233ab5e7f87272614c99ebced46c55f732b71dc105c6e7adc56e433be57871\"}\n[theanine-p22214254] The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. (2011). https://pubmed.ncbi.nlm.nih.gov/22214254/","model_system":"Randomized double-blind placebo-controlled actigraphy trial","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [theanine-p22214254] The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. (2011). https://pubmed.ncbi.nlm.nih.gov/22214254/","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"e2bf3fc8-fc9a-5d50-937a-559a76f8be7d","stable_key":"import-8f12ba85-1a92-5337-a9c0-9cee9b3be90d","title":"L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text.","file_path":"","sha256":"c78f2a1961da546cd8d3ae9131a16613aed0d1032904ca19175b0641647142c1","revision_id":"4ec64995-1e5b-5279-9102-f203cb2e29e5","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}