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(2019). https://pubmed.ncbi.nlm.nih.gov/31199458/ DOI: 10.1210/jc.2019-00207","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Human circulating measurements","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"750658eb-c621-5d76-b5e3-17cee3a91a5b","evidence_kind":"source_excerpt","locator":"Lines 1457-1468","start_line":1457,"end_line":1468,"excerpt":"### vd-martineau-24-ratio\nThe 24R, 25(OH)2D3: 25(OH)D3 ratio rose within both D2 and D3 groups, but their postsupplementation ratios did not differ significantly.\nCondition category: normal\nnutrient_topic: Vitamin D2 and D3 research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Both groups showed a catabolic-ratio increase; the between-form difference was not detected.\norganism: Homo sapiens\ntissue_or_cell_type: Human circulating measurements\nexperimental_model: 52-person metabolite-profile subset of a 340-person randomized trial; four 2.5 mg oral D2/D3 boluses over 4 months\nlimitations: Metabolite-to-parent ratios integrate production, binding, distribution and clearance; they are not an isolated CYP activity assay.\nexposure: Four oral 2.5 mg D2 or D3 bolus doses over 4 months.\ncross_nutrient: false\n[martineau2019] Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial. 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