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The appetite endpoint is rodent, and intraperitoneal administration is not a dietary exposure.\nexposure: Colonic and intraperitoneal acetate, and carbon-13 labelled fermentable carbohydrate\nevidence_span: {\"source_cache\": \"artifacts/acetate-research/24781306.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"4a1cc3cf5135e5856a281cd391c82611caa57afa2f837b0343cf048bb2c11e97\", \"start_char\": 0, \"end_char\": 1135, \"text_sha256\": \"4a1cc3cf5135e5856a281cd391c82611caa57afa2f837b0343cf048bb2c11e97\"}\n[acetate-p24781306] The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. 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