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The oncogenic pathway activation is measured in a model, not in treated patients.\nexposure: Alcohol exposure on an ALDH2-deficient background\nevidence_span: {\"source_cache\": \"artifacts/alcohol-research/31279903.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"3a0e9d2f127fd9454b41431aa6ed4bdcfd30723cc3acee2a1678015ac5299887\", \"start_char\": 0, \"end_char\": 2706, \"text_sha256\": \"3a0e9d2f127fd9454b41431aa6ed4bdcfd30723cc3acee2a1678015ac5299887\"}\n[alcohol-p31279903] ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles. 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