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Lower NTBI is not proof that standard chelation can be replaced or that hepcidin mediates the change.\nexposure: Two 500-mg capsules per day, total 1000 mg/day, for 12 weeks; placebo comparison\nevidence_span: {\"source_cache\": \"artifacts/curcumin-research/29806132.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"d000b66ecff021e755bef4a69beb4e1699039b55f1af96844c7860bae4b1847c\", \"start_char\": 0, \"end_char\": 1511, \"text_sha256\": \"d000b66ecff021e755bef4a69beb4e1699039b55f1af96844c7860bae4b1847c\"}\n[curcumin-p29806132] An investigation of the effects of curcumin on iron overload, hepcidin level, and liver function in β-thalassemia major patients: A double-blind randomized controlled clinical trial. 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