{"id":"b4c9412a-d770-5e45-b572-882d35326bcf","stable_key":"16c35a72-8162-5bb1-ae01-45331b8b42d0:moringa-type2-diabetes-dose-null","predicate":"does_not_change_after_adjustment","statement":"In a 40-person, 14-day randomized study of 20, 40 or 60 g/day Moringa leaves, adjusted end-of-intervention glucose, blood-pressure and lipid outcomes did not differ significantly among groups and changes were not dose-dependent.","claim_class":"observational","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"92a3ba1c-4755-5cbd-9876-1088e29d1ac3","mechanism_event_label":"In a 40-person, 14-day randomized study of 20, 40 or 60 g/day Moringa leaves, adjusted end-of-intervention glucose, blood-pressure and lipid outcomes did not differ significantly among groups and changes were not dose-dependent.","subject":{"id":"76b5830c-46c1-5df3-be10-cb766f9f796a","slug":"fresh-moringa-leaves","display_name":"Fresh Moringa leaves as eaten in the 14-day diabetes trial","entity_type_key":"botanical"},"object":{"id":"3aee505f-a4e5-5927-847a-a63dc63b5a55","slug":"human-type2-diabetes-glucose-bp-lipid-panel","display_name":"Glucose, blood-pressure and lipid panel in adults with type 2 diabetes","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"92a3ba1c-4755-5cbd-9876-1088e29d1ac3","stable_key":"16c35a72-8162-5bb1-ae01-45331b8b42d0:moringa-type2-diabetes-dose-null-event","event_type":"observed_relationship","label":"In a 40-person, 14-day randomized study of 20, 40 or 60 g/day Moringa leaves, adjusted end-of-intervention glucose, blood-pressure and lipid outcomes did not differ significantly among groups and changes were not dose-dependent.","description":"In a 40-person, 14-day randomized study of 20, 40 or 60 g/day Moringa leaves, adjusted end-of-intervention glucose, blood-pressure and lipid outcomes did not differ significantly among groups and changes were not dose-dependent.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"76b5830c-46c1-5df3-be10-cb766f9f796a","slug":"fresh-moringa-leaves","display_name":"Fresh Moringa leaves as eaten in the 14-day diabetes trial","entity_type_key":"botanical"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"3aee505f-a4e5-5927-847a-a63dc63b5a55","slug":"human-type2-diabetes-glucose-bp-lipid-panel","display_name":"Glucose, blood-pressure and lipid panel in adults with type 2 diabetes","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"dose","value_text":"0, 20, 40 or 60 g/day Moringa leaves with food","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"duration","value_text":"14 days","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"Primary PubMed abstract and indexed metadata reviewed. 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(2025). https://pubmed.ncbi.nlm.nih.gov/37229639/ DOI: 10.1177/02601060231176873","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"route","value_text":"Oral food","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue","value_text":"Fasting glucose, blood pressure and lipid profile","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"af58e54f-12b6-5e91-9311-81c8504a0eb7","evidence_kind":"source_excerpt","locator":"Lines 167-176","start_line":167,"end_line":176,"excerpt":"## moringa-type2-diabetes-dose-null\nIn a 40-person, 14-day randomized study of 20, 40 or 60 g/day Moringa leaves, adjusted end-of-intervention glucose, blood-pressure and lipid outcomes did not differ significantly among groups and changes were not dose-dependent.\nModel/species: Forty adults with type 2 diabetes\nTissue/system: Fasting glucose, blood pressure and lipid profile\nExposure: 0, 20, 40 or 60 g/day Moringa leaves with food\nRoute: Oral food\nDuration: 14 days\nLimits: The trial was small and short; within-group changes do not override the adjusted null between-group result.\nPrimary reference: Effects of Moringa oleifera leaves on the blood glucose, blood pressure, and lipid profile of type 2 diabetic subjects: A parallel group randomized clinical trial of efficacy. (2025). https://pubmed.ncbi.nlm.nih.gov/37229639/ DOI: 10.1177/02601060231176873\nAccess: Primary PubMed abstract and indexed metadata reviewed. Full-text method details not stated here remain unresolved.","model_system":"Forty adults with type 2 diabetes","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Exact original curation span with primary citation; not a publisher quotation.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"2752e9b3-e4b9-55fe-be07-944204cca4b8","stable_key":"import-16c35a72-8162-5bb1-ae01-45331b8b42d0","title":"Moringa oleifera: mechanism of action and interactions (2026-09-20)","document_type":"imported_text","citation_label":"Original AI-assisted source-specific curation with primary-study citations, model, exposure, route, duration, negative findings and limitations preserved. 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