{"id":"b4a68aae-dcf5-5b43-89e1-66f9dcdadeea","stable_key":"4fef8d72-f107-5eb5-b2fb-483ca85465e0:k2-ggcx-factor-defect","predicate":"pathogenic_variants_impair","statement":"The GGCX case had combined vitamin K-dependent factor deficiency; vitamin K substitution only partly normalized factor levels.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"9a9fa02c-46a1-5cd2-89e6-1e72a6c8da0e","mechanism_event_label":"The nutrient cannot necessarily repair the protein that uses it.","subject":{"id":"8889bae4-1223-5f80-b651-0c42190322a9","slug":"ggcx","display_name":"Gamma-glutamyl carboxylase / GGCX","entity_type_key":"protein"},"object":{"id":"39a27768-c200-5eb4-8654-439136f8eb68","slug":"coagulation-factor-function","display_name":"Vitamin K-dependent coagulation protein function","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"9a9fa02c-46a1-5cd2-89e6-1e72a6c8da0e","stable_key":"4fef8d72-f107-5eb5-b2fb-483ca85465e0:k2-ggcx-factor-defect-event","event_type":"biochemical_relationship","label":"The nutrient cannot necessarily repair the protein that uses it.","description":"The GGCX case had combined vitamin K-dependent factor deficiency; 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