{"id":"b120b85a-78fc-5457-a365-286ebadcad18","stable_key":"1acdb1e8-2159-5c7f-b39f-0153ff8024ae:taurine-fmo1-deletion","predicate":"deletion_alters","statement":"Fmo1-null mice accumulated urinary hypotaurine and had less urinary taurine than wild-type mice.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"d288e7dc-7f90-5c47-a9ff-cc44f4cf088d","mechanism_event_label":"Disabling the final enzyme changed the precursor/product pattern.","subject":{"id":"af476d81-a5a1-533a-927d-e459ea1e4c5f","slug":"mouse-fmo1","display_name":"Mouse flavin-containing monooxygenase 1 / Fmo1","entity_type_key":"protein"},"object":{"id":"1b0f6a54-417c-5b4b-9133-aff35b3aa39e","slug":"mouse-fmo1-urinary-metabolites","display_name":"Urinary hypotaurine and taurine in Fmo1-null mice","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"d288e7dc-7f90-5c47-a9ff-cc44f4cf088d","stable_key":"1acdb1e8-2159-5c7f-b39f-0153ff8024ae:taurine-fmo1-deletion-event","event_type":"observed_relationship","label":"Disabling the final enzyme changed the precursor/product pattern.","description":"Fmo1-null mice accumulated urinary hypotaurine and had less urinary taurine than wild-type mice.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"af476d81-a5a1-533a-927d-e459ea1e4c5f","slug":"mouse-fmo1","display_name":"Mouse flavin-containing monooxygenase 1 / Fmo1","entity_type_key":"protein"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"1b0f6a54-417c-5b4b-9133-aff35b3aa39e","slug":"mouse-fmo1-urinary-metabolites","display_name":"Urinary hypotaurine and taurine in Fmo1-null mice","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"eeff5174-9aa8-5f34-b107-e826edde648c","slug":"hypotaurine","display_name":"Hypotaurine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""},{"entity":{"id":"e423cd36-f183-522b-a5e4-5f9ef50eee7e","slug":"taurine","display_name":"Taurine","entity_type_key":"small_molecule"},"role":"context_participant","stoichiometry":null,"state_label":"","sequence_order":3,"notes":""}]},"contexts":[{"dimension":"availability_state","value_text":"machinery_impairment","comparator":null,"unit":null,"notes":"Imported condition classification; 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