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A low-dose challenge may not represent ordinary drinking.\nexposure: Low-dose alcohol challenge across ADH1B and ALDH2 genotypes\nevidence_span: {\"source_cache\": \"artifacts/alcohol-research/25365528.abstract.txt\", \"locator\": \"Indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"74fa331e891fe46dedf3789025686318b37eae41389f093bda084e4a6d482218\", \"start_char\": 0, \"end_char\": 1803, \"text_sha256\": \"74fa331e891fe46dedf3789025686318b37eae41389f093bda084e4a6d482218\"}\n[alcohol-p25365528] ALDH2*2 but not ADH1B*2 is a causative variant gene allele for Asian alcohol flushing after a low-dose challenge: correlation of the pharmacokinetic and pharmacodynamic findings. (2014). https://pubmed.ncbi.nlm.nih.gov/25365528/ DOI: 10.1097/fpc.0000000000000096","model_system":"Low-dose alcohol challenge in genotyped subjects with paired pharmacokinetics and pharmacodynamics","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [alcohol-p25365528] ALDH2*2 but not ADH1B*2 is a causative variant gene allele for Asian alcohol flushing after a low-dose challenge: correlation of the pharmacokinetic and pharmacodynamic findings. 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