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(2015). https://pubmed.ncbi.nlm.nih.gov/26228630/ DOI: 10.1248/bpb.b15-00402","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Kidney","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"4c84160c-9f25-5486-9551-9b5080bc5e4a","evidence_kind":"source_excerpt","locator":"Lines 939-950","start_line":939,"end_line":950,"excerpt":"### mangiferin-rat-slc2a9\nMangiferin reduced renal Rat glucose transporter 9 / Slc2a9 mRNA and protein in hyperuricemic rats.\nCondition category: normal\nnutrient_topic: Mangiferin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Less of a urate-reabsorption transporter was measured.\norganism: Rattus norvegicus for transporter findings\ntissue_or_cell_type: Kidney\nexperimental_model: Experimental hyperuricemia in rodents\nlimitations: Abundance changes do not prove direct transporter blockade or clinical gout efficacy.\nexposure: Mangiferin 1.5-24 mg/kg; potassium-oxonate rat model\nevidence_span: {\"source_cache\": \"artifacts/mangiferin-research/26228630.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"d7d497620fe96b2161af66b3d58b0a4ef8208f10f6d669fc680b85aa38b8d85c\", \"start_char\": 0, \"end_char\": 1633, \"text_sha256\": \"d7d497620fe96b2161af66b3d58b0a4ef8208f10f6d669fc680b85aa38b8d85c\"}\n[mangiferin-p26228630] Mangiferin Inhibits Renal Urate Reabsorption by Modulating Urate Transporters in Experimental Hyperuricemia. 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