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(1990). https://pubmed.ncbi.nlm.nih.gov/2351872/ DOI: 10.1016/s0022-2275(20)42836-6","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma chylomicron or VLDL fractions","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"beae733e-127f-50cc-86af-78ad2957070c","evidence_kind":"source_excerpt","locator":"Lines 311-322","start_line":311,"end_line":322,"excerpt":"### ve-transport-vldl-stereoisomers\nAfter equal oral labeled RRR- and SRR-alpha-tocopheryl acetate, human VLDL became enriched in RRR-alpha-tocopherol relative to SRR-alpha-tocopherol by 11 hours.\nCondition category: normal\nnutrient_topic: Vitamin E research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A later lipoprotein fraction favored the RRR form.\norganism: Homo sapiens\ntissue_or_cell_type: Plasma chylomicron or VLDL fractions\nexperimental_model: Human stable-isotope oral study with lipoprotein fractionation\nlimitations: Small tracer study; fraction enrichment alone does not prove the molecular sorting step or clinical benefit.\nexposure: Four subjects received equal paired doses of labeled RRR and SRR acetate ester with breakfast: 40, 50, 75 or 75 mg of each ester; samples through 76 hours.\ncross_nutrient: false\n[traber1990] RRR- and SRR-alpha-tocopherols are secreted without discrimination in human chylomicrons, but RRR-alpha-tocopherol is preferentially secreted in very low density lipoproteins. (1990). https://pubmed.ncbi.nlm.nih.gov/2351872/ DOI: 10.1016/s0022-2275(20)42836-6","model_system":"Human stable-isotope oral study with lipoprotein fractionation","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [traber1990] RRR- and SRR-alpha-tocopherols are secreted without discrimination in human chylomicrons, but RRR-alpha-tocopherol is preferentially secreted in very low density lipoproteins. 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