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(2004). https://pubmed.ncbi.nlm.nih.gov/15137922/ DOI: 10.1079/bjn20041105","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Plasma response","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"1038ba45-8a6e-59fd-b7a4-b1cffa7a91cd","evidence_kind":"source_excerpt","locator":"Lines 795-806","start_line":795,"end_line":806,"excerpt":"### zeaxanthin-ester-human-response\nThe dipalmitate preparation produced a higher plasma-response AUC than the free preparation in this crossover trial.\nCondition category: normal\nnutrient_topic: Zeaxanthin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Chemical form changed the measured response to this meal.\norganism: 12 volunteers\ntissue_or_cell_type: Plasma response\nexperimental_model: Randomized single-blind crossover meal trial\nlimitations: Meal- and formulation-specific response; no proof of disease prevention or an optimal universal formulation.\nexposure: 5 mg free zeaxanthin equivalents as free pigment or dipalmitate in yoghurt/breakfast; 24 h sampling\nevidence_span: {\"source_cache\": \"artifacts/zeaxanthin-research/15137922.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"6410a0f5d52cf32390f90f59a7b17d2340a889f888836129f8a93482ca055be0\", \"start_char\": 0, \"end_char\": 1847, \"text_sha256\": \"6410a0f5d52cf32390f90f59a7b17d2340a889f888836129f8a93482ca055be0\"}\n[zeaxanthin-p15137922] Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. (2004). https://pubmed.ncbi.nlm.nih.gov/15137922/ DOI: 10.1079/bjn20041105","model_system":"Randomized single-blind crossover meal trial","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [zeaxanthin-p15137922] Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. 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