{"id":"a1b253cf-876c-5e8d-adf3-bf4466f7c13f","stable_key":"79018983-9179-5c1a-8e7a-d6f47a13582b:ki-expectorant","predicate":"proposed_to_reduce","statement":"The label proposes increased respiratory secretions as the basis of KI expectorant action.","claim_class":"hypothesis_link","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"b68dccb3-e0b1-55b5-97d9-19d41462c05a","mechanism_event_label":"An expectorant mechanism is proposed, but its molecular target is unresolved.","subject":{"id":"d6a7fe6a-d90e-5fad-acf4-4971b24fa8d7","slug":"potassium-iodide","display_name":"Potassium iodide","entity_type_key":"chemical_species"},"object":{"id":"95791508-f972-5ed7-be36-f4ab932aa077","slug":"respiratory-mucus-viscosity","display_name":"Respiratory mucus viscosity","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"b68dccb3-e0b1-55b5-97d9-19d41462c05a","stable_key":"79018983-9179-5c1a-8e7a-d6f47a13582b:ki-expectorant-event","event_type":"observed_relationship","label":"An expectorant mechanism is proposed, but its molecular target is unresolved.","description":"The label proposes increased respiratory secretions as the basis of KI expectorant action.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"d6a7fe6a-d90e-5fad-acf4-4971b24fa8d7","slug":"potassium-iodide","display_name":"Potassium iodide","entity_type_key":"chemical_species"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"95791508-f972-5ed7-be36-f4ab932aa077","slug":"respiratory-mucus-viscosity","display_name":"Respiratory mucus viscosity","entity_type_key":"cellular_process"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"experimental_model","value_text":"2025 SSKI manufacturer label; 1 g KI/mL formulation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure_category","value_text":"Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Manufacturer hypothesis; DailyMed listing is not evidence of FDA approval or modern trial validation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions.","comparator":null,"unit":null,"notes":"","entity":{"slug":"potassium-iodide","display_name":"Potassium iodide","entity_type_key":"chemical_species"}},{"dimension":"plain_language","value_text":"An expectorant mechanism is proposed, but its molecular target is unresolved.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"SSKI product label, July 2025 · manufacturer label; DailyMed lists UNAPPROVED DRUG OTHER; not a trial or FDA approval · https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ca1d3449-ea29-49a4-8863-365ec95f1553","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"78e0c2bb-2155-512a-bd4f-6574985519ed","evidence_kind":"source_excerpt","locator":"Lines 464-470","start_line":464,"end_line":470,"excerpt":"## ki-expectorant\nAn expectorant mechanism is proposed, but its molecular target is unresolved.\nThe label proposes increased respiratory secretions as the basis of KI expectorant action.\nModel: 2025 SSKI manufacturer label; 1 g KI/mL formulation.\nLimitations: Manufacturer hypothesis; DailyMed listing is not evidence of FDA approval or modern trial validation.\nEvidence location: Primary abstract\nSSKI product label, July 2025 · manufacturer label; DailyMed lists UNAPPROVED DRUG OTHER; not a trial or FDA approval · https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ca1d3449-ea29-49a4-8863-365ec95f1553","model_system":"2025 SSKI manufacturer label; 1 g KI/mL formulation.","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Curation paraphrase; primary evidence location and source kind retained above.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"dc3ce411-f68f-5eb8-87c1-1592665f9cb6","stable_key":"import-79018983-9179-5c1a-8e7a-d6f47a13582b","title":"Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary-study references, chemical references and label statements individually identified. 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