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(2009). https://pubmed.ncbi.nlm.nih.gov/19228401/ DOI: 10.1186/1550-2783-6-6","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Serum and muscle metabolites, body composition and performance","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"trigger_kind","value_text":"biomarker_context","comparator":null,"unit":null,"notes":"Imported condition classification; unverified.","entity":null}],"evidence":[{"id":"80f405a3-f4bb-5864-824c-a3fa0bbe74d3","evidence_kind":"source_excerpt","locator":"Lines 1101-1112","start_line":1101,"end_line":1112,"excerpt":"### creatine-ethyl-ester-creatinine\nSerum creatinine was higher with creatine ethyl ester than with monohydrate or placebo at the measured post-baseline visits.\nCondition category: biomarker_context\nnutrient_topic: Creatine research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: A formulation can change the creatinine marker; this trial alone does not establish the mechanism or diagnose kidney injury.\norganism: 30 previously non-resistance-trained men\ntissue_or_cell_type: Serum and muscle metabolites, body composition and performance\nexperimental_model: Seven-week randomized double-blind comparison plus resistance training\nlimitations: The abstract conclusion overstates some comparisons: reported muscle total creatine did not differ significantly between formulations. This curation preserves the actual reported outcomes.\nexposure: Creatine ethyl ester, creatine monohydrate or placebo with loading and maintenance\nevidence_span: {\"source_cache\": \"artifacts/creatine-research/19228401.abstract.txt\", \"locator\": \"Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"381c3f18fe14f7eba6ee3abe9ca81ab4f02c293c3dd4593ea27dcbb6f879a114\", \"start_char\": 0, \"end_char\": 1727, \"text_sha256\": \"381c3f18fe14f7eba6ee3abe9ca81ab4f02c293c3dd4593ea27dcbb6f879a114\"}\n[creatine-p19228401] The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels. 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