{"id":"9c2d1a5c-ca89-5cba-a802-0ecb0e8593e3","stable_key":"e1af6d55-ced5-56c9-9a2d-8cc2ae6ec3ff:nasunin-ferric-complex","predicate":"forms_complex_with","statement":"Spectrophotometry indicated a 2:1 nasunin:Fe(III) complex.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"847b3c29-0028-5208-a9e4-00a0b19c9a9a","mechanism_event_label":"Binding iron can change its chemical availability.","subject":{"id":"6553997f-f098-5507-95b4-0fdb8aac491d","slug":"nasunin","display_name":"Nasunin","entity_type_key":"small_molecule"},"object":{"id":"964be7ac-43bd-5f3e-8326-94f0590de67a","slug":"iron-iii","display_name":"Ferric iron","entity_type_key":"ion"},"evidence_count":1,"mechanism_event":{"id":"847b3c29-0028-5208-a9e4-00a0b19c9a9a","stable_key":"e1af6d55-ced5-56c9-9a2d-8cc2ae6ec3ff:nasunin-ferric-complex-event","event_type":"biochemical_relationship","label":"Binding iron can change its chemical availability.","description":"Spectrophotometry indicated a 2:1 nasunin:Fe(III) complex.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"9cf95abc-7d5d-58e0-be72-a967fee3ba81","slug":"nasunin-ferric-complex","display_name":"Nasunin-ferric iron complex, 2:1 assay stoichiometry","entity_type_key":"chemical_species"},"role":"measured_complex","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"6553997f-f098-5507-95b4-0fdb8aac491d","slug":"nasunin","display_name":"Nasunin","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""},{"entity":{"id":"964be7ac-43bd-5f3e-8326-94f0590de67a","slug":"iron-iii","display_name":"Ferric iron","entity_type_key":"ion"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":2,"notes":""}]},"contexts":[{"dimension":"evidence_span","value_text":"{\"source_cache\": \"artifacts/nasunin-research/10100509.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c9b0aa305d8c03dd6b8fe8c1fae505dc50b3347a43c00387e01d4e36ecd04c09\", \"start_char\": 0, \"end_char\": 1400, \"text_sha256\": \"c9b0aa305d8c03dd6b8fe8c1fae505dc50b3347a43c00387e01d4e36ecd04c09\"}","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"ESR spin trapping, spectrophotometry and tissue-homogenate oxidation","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"exposure","value_text":"Nasunin isolated from Chouja eggplant; 1 micromolar homogenate experiment","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Homogenates do not establish brain entry or neuronal protection after oral intake. SOD-equivalent units are assay calibration, not SOD induction.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Nasunin research collection; topical membership is not evidence of a direct dietary effect.","comparator":null,"unit":null,"notes":"","entity":{"slug":"nasunin","display_name":"Nasunin","entity_type_key":"small_molecule"}},{"dimension":"organism","value_text":"Cell-free chemistry and rat brain homogenates","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"plain_language","value_text":"Binding iron can change its chemical availability.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"[nasunin-p10100509] Antioxidant activity of nasunin, an anthocyanin in eggplant. (1998). https://pubmed.ncbi.nlm.nih.gov/10100509/","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"tissue_or_cell_type","value_text":"Iron complex formation and lipid oxidation","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"94c75bb0-1b23-59d2-a0d7-7a8945c8e5ce","evidence_kind":"source_excerpt","locator":"Lines 536-547","start_line":536,"end_line":547,"excerpt":"### nasunin-ferric-complex\nSpectrophotometry indicated a 2:1 nasunin:Fe(III) complex.\nCondition category: normal\nnutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect.\nplain_language: Binding iron can change its chemical availability.\norganism: Cell-free chemistry and rat brain homogenates\ntissue_or_cell_type: Iron complex formation and lipid oxidation\nexperimental_model: ESR spin trapping, spectrophotometry and tissue-homogenate oxidation\nlimitations: Homogenates do not establish brain entry or neuronal protection after oral intake. SOD-equivalent units are assay calibration, not SOD induction.\nexposure: Nasunin isolated from Chouja eggplant; 1 micromolar homogenate experiment\nevidence_span: {\"source_cache\": \"artifacts/nasunin-research/10100509.abstract.txt\", \"locator\": \"Primary indexed abstract; zero-based, end-exclusive Unicode character offsets\", \"file_sha256\": \"c9b0aa305d8c03dd6b8fe8c1fae505dc50b3347a43c00387e01d4e36ecd04c09\", \"start_char\": 0, \"end_char\": 1400, \"text_sha256\": \"c9b0aa305d8c03dd6b8fe8c1fae505dc50b3347a43c00387e01d4e36ecd04c09\"}\n[nasunin-p10100509] Antioxidant activity of nasunin, an anthocyanin in eggplant. (1998). https://pubmed.ncbi.nlm.nih.gov/10100509/","model_system":"ESR spin trapping, spectrophotometry and tissue-homogenate oxidation","directness":"author_interpretation","verification_status":"source_derived_draft","notes":"Exact curation-document quotation, not publisher quotation. Study references: [nasunin-p10100509] Antioxidant activity of nasunin, an anthocyanin in eggplant. (1998). https://pubmed.ncbi.nlm.nih.gov/10100509/","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"2c43df19-ccb0-58f1-b9a4-bc92cda6de5a","stable_key":"import-e1af6d55-ced5-56c9-9a2d-8cc2ae6ec3ff","title":"Nasunin: identity, redox chemistry and nutrient connections (2026-09-17)","document_type":"imported_text","citation_label":"AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text.","file_path":"","sha256":"56552c208433294bf9a6c95513d981dbe4d00fd8336c121816d7b8bd6604d50e","revision_id":"b0296d49-32d7-52dc-a23c-5e862da0fba3","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}