{"id":"92a83779-e620-5149-80eb-0b47fb3283ac","stable_key":"33bef151-bdc7-5892-aff6-0345ab149739:nattokinase-enters-enterocytes-by-caveolae-mediated-endocytosis","predicate":"is_taken_up_by","statement":"Nystatin inhibited uptake in the same system, implicating a caveolae-mediated pathway.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"context_dependent","is_public":true,"mechanism_event_id":"bd440f11-46b8-554d-97ca-25058efca48e","mechanism_event_label":"Nystatin inhibited uptake in the same system, implicating a caveolae-mediated pathway.","subject":{"id":"6b03a125-209a-5060-8b35-ec9e0e54033c","slug":"nattokinase","display_name":"Nattokinase / subtilisin NAT","entity_type_key":"peptide"},"object":{"id":"1355815c-d749-593b-a460-eeae3f071385","slug":"caveolae-lipid-raft-endocytosis","display_name":"Caveolae/lipid-raft-associated endocytosis","entity_type_key":"cellular_process"},"evidence_count":1,"mechanism_event":{"id":"bd440f11-46b8-554d-97ca-25058efca48e","stable_key":"33bef151-bdc7-5892-aff6-0345ab149739:nattokinase-enters-enterocytes-by-caveolae-mediated-endocytosis-event","event_type":"biochemical_relationship","label":"Nystatin inhibited uptake in the same system, implicating a caveolae-mediated pathway.","description":"Intestinal epithelium","status":"provisional","compartment":null,"participants":[{"entity":{"id":"6b03a125-209a-5060-8b35-ec9e0e54033c","slug":"nattokinase","display_name":"Nattokinase / subtilisin NAT","entity_type_key":"peptide"},"role":"acting component","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"1355815c-d749-593b-a460-eeae3f071385","slug":"caveolae-lipid-raft-endocytosis","display_name":"Caveolae/lipid-raft-associated endocytosis","entity_type_key":"cellular_process"},"role":"component the finding is about","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"duration","value_text":"Not stated here","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"evidence_access","value_text":"Primary PubMed abstract and indexed metadata reviewed. 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