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species, compartment, exposure, co-substrates and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"agmatine-sulfate","display_name":"Agmatine Sulfate","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"Agmatine can feed polyamine metabolism in a defined preparation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Transport and metabolism of agmatine in rat hepatocyte cultures. · 2001 · https://pubmed.ncbi.nlm.nih.gov/11179960/ · DOI 10.1046/j.1432-1327.2001.01955.x","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"0afc7192-28d7-58a9-9bb7-d92edb50e9ba","evidence_kind":"source_excerpt","locator":"Lines 100-106","start_line":100,"end_line":106,"excerpt":"## agmatine-sulfate-rat-polyamine-production\nAgmatine can feed polyamine metabolism in a defined preparation.\nAbout 10% of taken-up agmatine label entered the polyamine pool in rat hepatocyte cultures.\nModel: Primary rat hepatocytes with radiotracer.\nLimitations: The abstract reports a polyamine pool, not a putrescine-only percentage or purified human AGMAT reaction.\nEvidence access: Primary abstract\nTransport and metabolism of agmatine in rat hepatocyte cultures. · 2001 · https://pubmed.ncbi.nlm.nih.gov/11179960/ · DOI 10.1046/j.1432-1327.2001.01955.x","model_system":"Primary rat hepatocytes with radiotracer.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; 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