{"id":"90a0fdae-18ea-5ae5-ab22-e7febadfe325","stable_key":"e3f6ce02-0bd7-5103-acc1-68503ab6751b:alcar-identity","predicate":"reported_relationship","statement":"ALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.","claim_class":"identity","status":"source_recorded","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"559a6be9-83f9-56bd-98bf-c71cdbd319b0","mechanism_event_label":"ALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.","subject":{"id":"5ce394a9-6ec6-56dd-866f-37d85c0556e4","slug":"acetylcarnitine","display_name":"Acetyl-L-carnitine","entity_type_key":"small_molecule"},"object":{"id":"6e34c035-9371-578f-b799-fd2a14e9e40f","slug":"l-carnitine","display_name":"L-Carnitine","entity_type_key":"small_molecule"},"evidence_count":1,"mechanism_event":{"id":"559a6be9-83f9-56bd-98bf-c71cdbd319b0","stable_key":"e3f6ce02-0bd7-5103-acc1-68503ab6751b:alcar-identity-event","event_type":"experimental_observation","label":"ALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.","description":"### alcar-identity\n\nALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.\nChEBI 57589 records formula C9H17NO4 and net charge zero. Net zero does not mean uncharged functional groups or unrestricted lipid diffusion. Hydrochloride salt mass differs from free ALCAR.\nModel and exposure: Chemical identity at near-neutral physiological conditions.\nLimitations: Limited to the recorded preparation, model, exposure and endpoint. Does not establish a human dietary deficiency, clinical benefit or unique molecular mediation.\nReference: ChEBI 57589: O-acetyl-L-carnitine | accessed 2026-10-06 | https://www.ebi.ac.uk/chebi/CHEBI:57589 | Access: Official chemical identity record; not a biological experiment.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"5ce394a9-6ec6-56dd-866f-37d85c0556e4","slug":"acetylcarnitine","display_name":"Acetyl-L-carnitine","entity_type_key":"small_molecule"},"role":"recorded factor","stoichiometry":null,"state_label":"as reported","sequence_order":0,"notes":""},{"entity":{"id":"6e34c035-9371-578f-b799-fd2a14e9e40f","slug":"l-carnitine","display_name":"L-Carnitine","entity_type_key":"small_molecule"},"role":"measured outcome","stoichiometry":null,"state_label":"not_reported","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Official chemical identity record; not a biological experiment.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Chemical identity at near-neutral physiological conditions.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"interpretation_status","value_text":"Source-derived curation with stated access limits; ungraded, not independent replication.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Limited to the recorded preparation, model, exposure and endpoint. Does not establish a human dietary deficiency, clinical benefit or unique molecular mediation.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Acetyl-L-carnitine collection; exact intervention and molecular form govern interpretation.","comparator":null,"unit":null,"notes":"","entity":{"slug":"acetylcarnitine","display_name":"Acetyl-L-carnitine","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"ALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"ChEBI 57589: O-acetyl-L-carnitine | https://www.ebi.ac.uk/chebi/CHEBI:57589","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"source_locator","value_text":"Reviewed reference alcar-identity; ChEBI 57589 records formula C9H17NO4 and net charge zero. Net zero does not mean uncharged functional groups or unrestricted lipid diffusion. Hydrochloride salt mass differs from free ALCAR.","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"5c2b60fb-874d-59e8-9f28-6af97eee63da","evidence_kind":"source_excerpt","locator":"Lines 15-21","start_line":15,"end_line":21,"excerpt":"### alcar-identity\n\nALCAR is the O-acetyl ester of L-carnitine; its zwitterionic structure has a positive quaternary ammonium and a negative carboxylate.\nChEBI 57589 records formula C9H17NO4 and net charge zero. Net zero does not mean uncharged functional groups or unrestricted lipid diffusion. Hydrochloride salt mass differs from free ALCAR.\nModel and exposure: Chemical identity at near-neutral physiological conditions.\nLimitations: Limited to the recorded preparation, model, exposure and endpoint. Does not establish a human dietary deficiency, clinical benefit or unique molecular mediation.\nReference: ChEBI 57589: O-acetyl-L-carnitine | accessed 2026-10-06 | https://www.ebi.ac.uk/chebi/CHEBI:57589 | Access: Official chemical identity record; not a biological experiment.","model_system":"Chemical identity at near-neutral physiological conditions.","directness":"reported_statement","verification_status":"source_recorded","notes":"Original paraphrase in the retained reviewed reference, not a verbatim primary-paper quotation. Access level is explicit.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"2588f904-245a-597a-8a12-65118013fb90","stable_key":"import-e3f6ce02-0bd7-5103-acc1-68503ab6751b","title":"Acetyl-L-carnitine: detailed mechanisms of action (reviewed 6 October 2026)","document_type":"imported_text","citation_label":"AI-assisted original review of primary studies and clearly identified official records. Exact primary access is stated; no independent replication is claimed.","file_path":"","sha256":"84cc82d6fbb0fd5d73c4ce779e9f88e7f0184ba2d29b18ad0f153815380f2975","revision_id":"dac7a950-dbe5-5c7a-9c70-2ea711d5c71a","review_status":"source_recorded","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}