{"id":"8d4d0dbb-7dab-5180-8159-67f1b47555e9","stable_key":"52871722-4aa6-5453-a902-3e76356db327:resveratrol-mitoneet-parent-null","predicate":"does_not_detectably_bind","statement":"Parent resveratrol showed no tendency to interact with mitoNEET in the reported binding experiments.","claim_class":"mechanistic","status":"source_derived_draft","evidence_grade":"ungraded","direction":"neutral","is_public":true,"mechanism_event_id":"baccbe9e-ff8b-5e76-9cd7-a999c4b0ed08","mechanism_event_label":"Do not transfer a metabolite target to the parent.","subject":{"id":"53549e32-e6b4-5f09-94e6-62867b015713","slug":"resveratrol","display_name":"Resveratrol","entity_type_key":"small_molecule"},"object":{"id":"9f517264-473e-5d48-bc12-c5b601f38915","slug":"cisd1","display_name":"Human mitoNEET / CISD1","entity_type_key":"protein"},"evidence_count":1,"mechanism_event":{"id":"baccbe9e-ff8b-5e76-9cd7-a999c4b0ed08","stable_key":"52871722-4aa6-5453-a902-3e76356db327:resveratrol-mitoneet-parent-null-event","event_type":"observed_relationship","label":"Do not transfer a metabolite target to the parent.","description":"Parent resveratrol showed no tendency to interact with mitoNEET in the reported binding experiments.","status":"provisional","compartment":null,"participants":[{"entity":{"id":"53549e32-e6b4-5f09-94e6-62867b015713","slug":"resveratrol","display_name":"Resveratrol","entity_type_key":"small_molecule"},"role":"subject","stoichiometry":null,"state_label":"","sequence_order":0,"notes":""},{"entity":{"id":"9f517264-473e-5d48-bc12-c5b601f38915","slug":"cisd1","display_name":"Human mitoNEET / CISD1","entity_type_key":"protein"},"role":"target","stoichiometry":null,"state_label":"","sequence_order":1,"notes":""}]},"contexts":[{"dimension":"evidence_access","value_text":"Primary abstract","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"experimental_model","value_text":"Same purified protein study.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"limitations","value_text":"Null applies to the tested conditions.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"nutrient_topic","value_text":"Resveratrol collection; molecular form, preparation, species, exposure and manipulation remain explicit.","comparator":null,"unit":null,"notes":"","entity":{"slug":"resveratrol","display_name":"Resveratrol","entity_type_key":"small_molecule"}},{"dimension":"plain_language","value_text":"Do not transfer a metabolite target to the parent.","comparator":null,"unit":null,"notes":"","entity":null},{"dimension":"primary_references","value_text":"Complexes of the outer mitochondrial membrane protein mitoNEET with resveratrol-3-sulfate. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21591687/ · DOI 10.1021/bi200546s","comparator":null,"unit":null,"notes":"","entity":null}],"evidence":[{"id":"dc724625-1df5-55b6-81f1-abb920d3d4d5","evidence_kind":"source_excerpt","locator":"Lines 134-140","start_line":134,"end_line":140,"excerpt":"## resveratrol-mitoneet-parent-null\nDo not transfer a metabolite target to the parent.\nParent resveratrol showed no tendency to interact with mitoNEET in the reported binding experiments.\nModel: Same purified protein study.\nLimitations: Null applies to the tested conditions.\nEvidence access: Primary abstract\nComplexes of the outer mitochondrial membrane protein mitoNEET with resveratrol-3-sulfate. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21591687/ · DOI 10.1021/bi200546s","model_system":"Same purified protein study.","directness":"reported_statement","verification_status":"source_derived_draft","notes":"Original curation paraphrase; evidence access and experimental limitations specified.","relationship":"supports","weight":1.0,"link_notes":"","source":{"id":"2844eda9-a122-5357-ae47-cd58227c5994","stable_key":"import-52871722-4aa6-5453-a902-3e76356db327","title":"Resveratrol: metabolites, target selectivity and cross-nutrient mechanisms (2026-09-19)","document_type":"imported_text","citation_label":"AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text.","file_path":"","sha256":"04885b4bee72f912a7f3f618f1b2bf79c944dbcb20500398c2729fc8228dcd9a","revision_id":"99504ff2-f1d3-5f4c-bc31-e1030d27a918","review_status":"unverified_draft","notes":""}}],"relations":[],"conflicts":[],"corrections":[],"research":null}